Omega-3 polyunsaturated fatty acids supplementation and cardiovascular outcomes: do formulation, dosage, and baseline cardiovascular risk matter? An updated …

M Casula, E Olmastroni, M Gazzotti, F Galimberti… - Pharmacological …, 2020 - Elsevier
The recent publication of the REDUCE-IT study has reopened the debate about the efficacy
of omega-3 fatty acids in reducing the risk of cardiovascular (CV) events. This meta-analysis …

Omega-3 polyunsaturated fatty acid supplementation in the prevention of cardiovascular disease

CP Walz, AR Barry… - … Journal/Revue des …, 2016 - journals.sagepub.com
Introduction: Omega-3 polyunsaturated fatty acids (PUFAs) have purported protective
cardiovascular (CV) effects. We sought to assess the evidence available for the use of …

Omega-3 fatty acid supplementation and cardiovascular disease risk: glass half full or time to nail the coffin shut?

KC Maki, MR Dicklin - Nutrients, 2018 - mdpi.com
There has been a great deal of controversy in recent years about the potential role of dietary
supplementation with long-chain omega-3 polyunsaturated fatty acids (n-3 PUFA) in the …

Comparative efficacy of omega-3 polyunsaturated fatty acids on major cardiovascular events: A network meta-analysis of randomized controlled trials

B Yang, PT Tseng, X Hu, BY Zeng, JPC Chang… - Progress in Lipid …, 2022 - Elsevier
The role of omega-3 polyunsaturated fatty acids (PUFAs) in primary and secondary
prevention on major cardiovascular events (MCE) is inconclusive due to the potential …

Effects of Omega-3 fatty acid on major cardiovascular events and mortality in patients with coronary heart disease: a meta-analysis of randomized controlled trials

YT Wen, JH Dai, Q Gao - Nutrition, Metabolism and Cardiovascular …, 2014 - Elsevier
Aim There is considerable discrepancy regarding the protective effects of Omega-3
polyunsaturated fatty acids (Omega-3 PUFAs) in patients with coronary heart disease (CHD) …

Omega-3 fatty acids and cardiovascular disease: are there benefits?

KJ Bowen, WS Harris, PM Kris-Etherton - Current treatment options in …, 2016 - Springer
Opinion statement Early secondary prevention trials of fish and omega-3 polyunsaturated
fatty acid (PUFA) capsules reported beneficial effects on cardiovascular disease (CVD) …

Do omega-3 polyunsaturated fatty acids prevent cardiovascular disease? A review of the randomized clinical trials

LM Kimmig, DG Karalis - Lipid Insights, 2013 - journals.sagepub.com
Fish oil is rich in the omega-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid
(EPA) and docosahexaenoic acid (DHA). Numerous epidemiological studies and several …

Omega-3 polyunsaturated fatty acids focusing on eicosapentaenoic acid and docosahexaenoic acid in the prevention of cardiovascular diseases: a review of the state …

Y Watanabe, I Tatsuno - Expert Review of Clinical Pharmacology, 2021 - Taylor & Francis
Introduction: An epidemiological study of Greenlandic Inuit suggested the importance of
omega-3 polyunsaturated fatty acids (PUFAs) in preventing ischemic heart disease. After …

Effects of omega-3, omega-6, and total dietary polyunsaturated fatty acids supplementation in patients with atherosclerotic cardiovascular disease: a systematic review …

S Luo, H Hou, Y Wang, Y Li, L Zhang, H Zhang… - Food & Function, 2023 - pubs.rsc.org
Background: Uncertainty exists about the link between omega-3 fatty acid, omega-6 fatty
acid, and total polyunsaturated fatty acid (PUFA) intake and mortality in atherosclerotic …

Does supplementation with omega-3 PUFAs add to the prevention of cardiovascular disease?

EC Rizos, MS Elisaf - Current Cardiology Reports, 2017 - Springer
Abstract Purpose of Review Omega-3 fatty acids are increasingly used for the protection of
cardiovascular disease. The main but not the sole mechanism of action is the reduction of …