The ability to measure biomarkers, both specifically and selectively at the single‐molecule
level in biological fluids, has the potential to transform the diagnosis, monitoring, and …

Nanopores are nanofluidic channels formed through thin membranes that can deliver
standout single-molecule and single-particle sensing capabilities. Analytical targets include …

Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

Nanopore sensors provide a highly innovative technique for a rapid and label-free single
molecule analysis, which holds a great potential in routing applications. Biological …

Sensing with chemically-modified nanopores is an emerging field that is expected to have
major impact on bioanalysis and fundamental understanding of nanoscale chemical …

The advent of single-molecule probing techniques has revolutionized the biomedical and
life science fields and has spurred the development of a new class of labs-on-chip based on …

Nanopore-based sensing is a powerful technique for the detection of diverse organic and
inorganic molecules, long-read sequencing of nucleic acids, and single-molecule analyses …

In the 90s, the development of a novel single molecule technique based on nanopore
sensing emerged. Preliminary improvements were based on the molecular or biological …

Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …

Highlights•Biological nanopores enable label-free single molecule sensing.•Nanopores
have great potential for low cost rapid DNA sequencing.•Improved artificial membrane …