COVID-19: The emerging immunopathological determinants for recovery or death

T Ahmad, R Chaudhuri, MC Joshi… - Frontiers in …, 2020 - frontiersin.org
Hyperactivation of the host immune system during infection by SARS-CoV-2 is the leading
cause of death in COVID-19 patients. It is also evident that patients who develop …

Pathophysiology and clinical management of coronavirus disease (COVID-19): a mini-review

Y Zhu, L Sharma, D Chang - Frontiers in Immunology, 2023 - frontiersin.org
An unprecedented global pandemic caused by a novel coronavirus named SARS-CoV-2
has created a severe healthcare threat and become one of the biggest challenges to human …

Innate immunology in COVID-19—a living review. Part II: dysregulated inflammation drives immunopathology

PRS Rodrigues, A Alrubayyi, E Pring… - Oxford open …, 2020 - academic.oup.com
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a global health crisis and will …

Innate immunity: the first line of defense against SARS-CoV-2

MS Diamond, TD Kanneganti - Nature immunology, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …

Towards treatment planning of COVID-19: Rationale and hypothesis for the use of multiple immunosuppressive agents: Anti-antibodies, immunoglobulins, and …

A Saghazadeh, N Rezaei - International immunopharmacology, 2020 - Elsevier
The novel coronavirus, SARS-CoV2, can cause a potentially fatal disease, COVID-19, in
humans. Here, we will provide an overview of therapeutic options for COVID-19. Plasma …

Pulmonary immune responses against SARS-CoV-2 infection: harmful or not?

A Guillon, PS Hiemstra, M Si-Tahar - Intensive Care Medicine, 2020 - Springer
Although our knowledge of the pulmonary immune response in patients with SARS-CoV-2
infection is still limited, intensivists will be offered to prescribe immunomodulatory …

[HTML][HTML] Role of the humoral immune response during COVID-19: guilty or not guilty?

M Yaugel-Novoa, T Bourlet, S Paul - Mucosal Immunology, 2022 - Elsevier
Systemic and mucosal humoral immune responses are crucial to fight respiratory viral
infections in the current pandemic of COVID-19 caused by the SARS-CoV-2 virus. During …

Innate and adaptive immune responses to SARS-CoV-2 in humans: relevance to acquired immunity and vaccine responses

SC Jordan - Clinical & Experimental Immunology, 2021 - academic.oup.com
The factors responsible for the spectrum of coronavirus 19 (COVID-19) disease severity and
the genesis and nature of protective immunity against COVID-19 remain elusive. Multiple …

[HTML][HTML] COVID-19: A state of art on immunological responses, mutations, and treatment modalities in riposte

X Gong, A Khan, MY Wani, A Ahmad, A Duse - Journal of Infection and …, 2023 - Elsevier
Over the last few years, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
unleashed a global public health catastrophe that had a substantial influence on human …

COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …