Background The prognosis of patients with colorectal cancer is related to early detection.
However, commonly used screening markers lack sensitivity and specificity. In this study, we …

BACKGROUND Detection of fecal DNA is a promising approach to colorectal cancer
screening. However, the sensitivity of current fecal DNA tests for colorectal polyps is low. We …

Objective: To identify methylated genes in serum with diagnostic potentials for early
colorectal cancer (CRC). Methods: Serum methylation levels of up to 12 genes were …

Aberrantly methylated genes are increasingly being established as biomarkers for the
detection of colorectal cancer (CRC). In the present study, the methylation levels of the …

Background and Aim Aberrant hypermethylation of cancer-related genes has emerged as a
promising strategy for the development of diagnostic, prognostic and predictive biomarkers …

DNA methylation, the modification of a cytosine nucleotide immediately preceding a guanine
base in a stretch of DNA, is rapidly gaining strength in the diagnostic field as a powerful tool …

Background: Sensitive, specific blood-based tests are difficult to develop unless steps are
taken to maximize performance characteristics at every stage of marker discovery and …

Abstract Changes in DNA methylation, whether hypo‐or hypermethylation, have been
shown to be associated with the progression of colorectal cancer. Methylation changes …

BACKGROUND: Colorectal cancer (CRC) is one of the leading causes of mortality and
morbidity in the world. It is characterized by different pathways of carcinogenesis and is a …

BACKGROUND: Pancreatic cancer (PanC) presents at late stage with high mortality.
Effective early detection methods are needed. Aberrantly methylated genes are unexplored …