Recent advancements in genome sequencing and bioinformatic analysis of fungal genomes
have revealed that fungi possess cryptic or silent biosynthetic gene clusters (BGCs). This …

Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …

Covering: up to 2019 Fungi produce a remarkable diversity of secondary metabolites: small,
bioactive molecules not required for growth but which are essential to their ecological …

Fungal species have the capability of producing an overwhelming diversity of bioactive
substances that can have beneficial but also detrimental effects on human health. These so …

Filamentous fungi are excellent sources for the production of a group of bioactive small
molecules which are often called secondary metabolites (SMs). The advanced genome …

Fungal secondary metabolites (SMs) represent an invaluable source of therapeutic drugs.
Genomics-based approaches to SM discovery have revealed a vast and largely untapped …

Microorganisms produce a wide range of natural products (NPs) with clinically and
agriculturally relevant biological activities. In bacteria and fungi, genes encoding successive …

The genomes of filamentous fungi contain up to 90 biosynthetic gene clusters (BGCs)
encoding diverse secondary metabolites—an enormous reservoir of untapped chemical …

Recent published sequencing of fungal genomes has revealed that these microorganisms
have a surprisingly large number of secondary metabolite pathways that can serve as …

Mining for novel natural compounds is of eminent importance owing to the continuous need
for new pharmaceuticals. Filamentous fungi are historically known to harbor the genetic …