An integrated sample-to-answer SERS platform for multiplex phenotyping of extracellular vesicles

W Lin, L Yuan, Z Gao, G Cai, C Liang, M Fan… - Sensors and Actuators B …, 2023 - Elsevier
Tumor-derived extracellular vesicles (EVs) are emerging as a non-invasive liquid biopsy
marker for cancer diagnosis and treatment monitoring. However, clinical detection …

Enabling sensitive phenotypic profiling of cancer-derived small extracellular vesicles using surface-enhanced Raman spectroscopy nanotags

W Zhang, L Jiang, RJ Diefenbach, DH Campbell… - ACS …, 2020 - ACS Publications
Circulating cancer-derived small extracellular vesicles (EVs) are nanoscale membranous
vesicles shed from cancer cells that are released into surrounding body fluids. Small EVs …

Emerging integrated SERS-microfluidic devices for analysis of cancer-derived small extracellular vesicles

L Ngo, A Tukova, A Hassanzadeh-Barforoushi… - Lab on a Chip, 2023 - pubs.rsc.org
Cancer-derived small extracellular vesicles (sEVs) are specific subgroups of lipid bilayer
vesicles secreted from cancer cells to the extracellular environment. They carry distinct …

MoS2-Plasmonic Nanocavities for Raman Spectra of Single Extracellular Vesicles Reveal Molecular Progression in Glioblastoma

M Jalali, C del Real Mata, L Montermini, O Jeanne… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are continually released from cancer cells into biofluids, carrying
actionable molecular fingerprints of the underlying disease with considerable diagnostic and …

Immuno-capture of extracellular vesicles for individual multi-modal characterization using AFM, SEM and Raman spectroscopy

P Beekman, A Enciso-Martinez, HS Rho, SP Pujari… - Lab on a Chip, 2019 - pubs.rsc.org
Tumor-derived extracellular vesicles (tdEVs) are promising blood biomarkers for cancer
disease management. However, blood is a highly complex fluid that contains multiple …

Single particle automated Raman trapping analysis of breast cancer cell-derived extracellular vesicles as cancer biomarkers

J Penders, A Nagelkerke, EM Cunnane, SV Pedersen… - ACS …, 2021 - ACS Publications
Extracellular vesicles (EVs) secreted by cancer cells provide an important insight into cancer
biology and could be leveraged to enhance diagnostics and disease monitoring. This paper …

[HTML][HTML] Breaking the classics: next-generation biosensors for the isolation, profiling and detection of extracellular vesicles

R Vaz, VM Serrano, Y Castaño-Guerrero… - … and Bioelectronics: X, 2022 - Elsevier
Extracellular vesicles (EVs) contain biomarkers that may represent a paradigm shift in timely
disease diagnosis and personalized therapeutic approaches. Despite tremendous progress …

New sensors for extracellular vesicles: insights on constituent and associated biomarkers

CZJ Lim, L Zhang, Y Zhang, NR Sundah, H Shao - ACS sensors, 2019 - ACS Publications
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles released by cells
into the circulation. As an emerging class of circulating biomarkers, EVs contain a trove of …

Space curvature-inspired nanoplasmonic sensor for breast cancer extracellular vesicle fingerprinting and machine learning classification

M Kazemzadeh, CL Hisey, A Artuyants… - Biomedical Optics …, 2021 - opg.optica.org
Extracellular vesicles (EVs) are micro and nanoscale lipid-enclosed packages that have
shown potential as liquid biopsy targets for cancer because their structure and contents …

Extracellular vesicle identification using label-free surface-enhanced raman spectroscopy: detection and signal analysis strategies

H Shin, D Seo, Y Choi - Molecules, 2020 - mdpi.com
Extracellular vesicles (EVs) have been widely investigated as promising biomarkers for the
liquid biopsy of diseases, owing to their countless roles in biological systems. Furthermore …