The role of CD8+ T cells in immune control of Trypanosoma cruzi infection in mice was
examined by using in vivo depletion of CD8+ T cells with antibodies. Both the resistant …

Infection with Trypanosoma cruzi decreases the ability of spleen cells from mice to respond
to either T cell, concanavalin A (Con A), or B cell, lipopolysaccharide (LPS), mitogens. The …

Recent in vivo depletion studies in mice demonstrated that CD8+ T cells play a critical role in
acute resistance to experimental Trypanosoma cruzi infections. As part of efforts to …

Using glycol methacrylate in conjunction with avidin-biotin-peroxidase com plex techniques,
we studied the contribution of T cell subsets to tissue inflammation during acute …

The kinetics of effector CD8+-T-cell responses to specific Trypanosoma cruzi epitopes was
investigated after challenge. Our results suggest that the delayed kinetics differs from that …

The immunobiology of Trypanosoma cruzi infection in mice is discussed under the following
headings: definition of the immunological problem; the experimental system; the …

CD8+ T cells are crucial to the control of Trypanosoma cruzi infection and probably act via
multiple mechanisms, the most important being the production of interferon‐γ (IFN‐γ). In the …

Parasite antigens released from Trypanosoma cruzi-infected cells were adsorbed to infected
and uninfected mammalian cells thus rendering them susceptible to immune lysis by …

Infection with Trypanosoma cruzi results in the development of both type 1 and type 2
patterns of cytokine responses during acute and chronic stages of infection. To investigate …

The role of T cell populations in immune control of Trypanosoma cruzi infection and
subsequent development of disease has been examined using gene knockout mice …