[引用][C] 839-3 Frequency, spectrum, and phenotype of hypertrophic cardiomyopathy patients with multiple sarcomeric mutations

SL Van Driest, SR Ommen, ML Will, VC Vasile… - Journal of the American …, 2004 - jacc.org
Background: Surgical septal myectomy is the definitive treatment for relief of drug-refractory
symptoms in hypertrophic cardiomyopathy (HCM). Recent data document reduced survival …

[引用][C] 839-1 The long-term effect of surgical myectomy on survival in patients with obstructive hypertrophic cardiomyopathy

SR Ommen, I Olivotto, MS Maron, S Betocchi… - Journal of the American …, 2004 - jacc.org
Background: Surgical septal myectomy is the definitive treatment for relief of drug-refractory
symptoms in hypertrophic cardiomyopathy (HCM). Recent data document reduced survival …

[引用][C] 839-4 Treatment with antioxidant N-acetylcysteine reverses interstitial fibrosis in a mouse model of human hypertrophic cardiomyopathy mutation

N Tsybouleva, T Halder, R Patel, S Lutucuta… - Journal of the American …, 2004 - jacc.org
Background: Surgical septal myectomy is the definitive treatment for relief of drug-refractory
symptoms in hypertrophic cardiomyopathy (HCM). Recent data document reduced survival …

Does surgical relief of obstruction improve prognosis for hypertrophic cardiomyopathy?

RE Ross, MV Sherrid, MM Casey, DG Swistel… - Progress in …, 2012 - Elsevier
Unique genetic characteristics of hypertrophic cardiomyopathy (HCM), including
heterogeneity and incomplete penetrance, have made making predictions about prognosis …

Patients with genotype-positive hypertrophic cardiomyopathy are at increased risk of heart failure related death

HG van Velzen, PA Vriesendorp, RA Oldenburg… - Journal of the American …, 2015 - jacc.org
Background: Pathogenic sarcomere mutations are found in about 50% of hypertrophic
cardiomyopathy (HCM) patients. Currently, clear genotype-phenotype relations are lacking …

SARCOMERE MUTATIONS DO NOT AGGRAVATE THE PROGNOSIS OF HYPERTROPHIC CARDIOMYOPATHY PATIENTS UNDERGOING SEPTAL MYECTOMY

J Zhang, C Song, C Zhu, K Yin, C Nie, Y Zhang… - Journal of the American …, 2022 - jacc.org
Background: Hypertrophic cardiomyopathy (HCM) is the most common monogenic heart
disease. The presence of sarcomere mutations is a powerful predictor of adverse outcomes …

Hypertrophic cardiomyopathy: clinical update

JB Geske, SR Ommen, BJ Gersh - JACC: heart failure, 2018 - jacc.org
Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiomyopathy,
manifesting as left ventricular hypertrophy in the absence of a secondary cause. The genetic …

[HTML][HTML] The diagnosis and treatment of hypertrophic cardiomyopathy

C Prinz, M Farr, D Hering, D Horstkotte… - Deutsches Ärzteblatt …, 2011 - ncbi.nlm.nih.gov
Methods In this article, we summarize the current state of the diagnosis and treatment of
HCM on the basis of a selective review of recent publications with relevance to clinical …

[HTML][HTML] Treating hypertrophic cardiomyopathy: two views

L Salberg - Journal of the American College of Cardiology, 2005 - jacc.org
I am writing in response to the published views in JACC regarding treatment of hypertrophic
cardiomyopathy (1). I am the president of the Hypertrophic Cardiomyopathy Association …

Clinical spectrum and management implications of left ventricular outflow obstruction with mild ventricular septal thickness in hypertrophic cardiomyopathy

EJ Rowin, BJ Maron, A Chokshi, M Kannappan… - The American Journal of …, 2018 - Elsevier
Hypertrophic cardiomyopathy (HC) has historically been characterized as a disease of
substantial left ventricular hypertrophy, often associated with dynamic left ventricular outflow …