Hyperthermia in combination with oxidative stress induces autophagic cell death in HT‐29 colon cancer cells

F Chen, CC Wang, E Kim… - Cell biology …, 2008 - Wiley Online Library
The purpose of this study was to evaluate the mechanism of ROS‐induced hyperthermic cell
death in a colon cancer cell line. HT‐29 colon cancer cells were exposed to heat (43° C) in …

[HTML][HTML] Heat shock increases levels of reactive oxygen species, autophagy and apoptosis

S Kassis, M Grondin, DA Averill-Bates - Biochimica et Biophysica Acta (BBA …, 2021 - Elsevier
Hyperthermia is a promising anticancer treatment used in combination with radiotherapy
and chemotherapy. Temperatures above 41.5° C are cytotoxic and hyperthermia treatments …

[HTML][HTML] Autophagic cell death induced by reactive oxygen species is involved in hyperthermic sensitization to ionizing radiation in human hepatocellular carcinoma …

GJ Yuan, JJ Deng, DD Cao, L Shi, X Chen… - World Journal of …, 2017 - ncbi.nlm.nih.gov
AIM To investigate whether autophagic cell death is involved in hyperthermic sensitization to
ionizing radiation in human hepatocellular carcinoma cells, and to explore the underlying …

Thermal sensitization through ROS modulation: a strategy to improve the efficacy of hyperthermic intraperitoneal chemotherapy

CC Wang, F Chen, E Kim, LE Harrison - Surgery, 2007 - Elsevier
BACKGROUND: The purpose of this study was to investigate whether modulation of cellular
reactive oxygen species (ROS) provides a synergistic effect with hyperthermia to induce …

A study of thermal dose-induced autophagy, apoptosis and necroptosis in colon cancer cells

PXE Mouratidis, I Rivens, G Ter Haar - International Journal of …, 2015 - Taylor & Francis
Purpose: The pleiotropic effects of heat on cancer cells have been well documented. The
biological effects seen depend on the temperature applied, and the heating duration. In this …

Hyperthermia enhances radiosensitivity of colorectal cancer cells through ROS inducing autophagic cell death

MC Ba, H Long, S Wang, YB Wu… - Journal of Cellular …, 2018 - Wiley Online Library
Hyperthermia (HT) enhances the anti‐cancer effects of radiotherapy (RT), but the precise
biochemical mechanisms involved are unclear. This study was aim to investigate if mild HT …

Mild hyperthermia enhances sensitivity of gastric cancer cells to chemotherapy through reactive oxygen species–induced autophagic death

MC Ba, H Long, SZ Cui, YF Gong, ZF Yan… - Tumor …, 2017 - journals.sagepub.com
Mild hyperthermia enhances anti-cancer effects of chemotherapy, but the precise
biochemical mechanisms involved are not clear. This study was carried out to investigate …

Oxidative stress as a necessary factor in room temperature-induced apoptosis of HL-60 cells

M Shimura, Y Osawa, A Yuo, K Hatake… - Journal of Leukocyte …, 2000 - academic.oup.com
HL-60 cells undergo apoptosis when placed at room temperature (RT)[Shimura et al.(1997)
FEBS Lett. 417, 379–384]. We report that superoxide anion radical, one of the reactive …

Proteasome inhibition potentiates the cytotoxic effects of hyperthermia in HT-29 colon cancer cells through inhibition of heat shock protein 27

F Chen, R Rezavi, CC Wang, LE Harrison - Oncology, 2008 - karger.com
Background: The purpose of this study was to investigate whether proteasome inhibition
acts as a thermal sensitizing agent to induce tumor cell death in a colon cancer cell line …

Enhancement of hyperthermia-induced apoptosis by modification of intracellular oxidative stress

ZGUO CUI, S WADA, T KONDO… - … (Japanese Journal of …, 2005 - jstage.jst.go.jp
Hyperthermia (HT) for cancer therapy combined with radiation and anticancer agents has
been clinically used and has shown good results to a certain extent. However, clinical …