Clinical research attempts to address a relatively straightforward, and important challenge:
how do we determine whether one medical intervention is better than another, whether it …

One plausible way to structure a narrative about the origin and development of medical
ethics is to see much of it as a commentary on the ethical issues that have arisen in …

Clinical research is thought to be ethically problematic and is subject to extensive regulation
and oversight. Despite frequent endorsement of this view, there has been almost no …

In her critique of research ethics, Rosamond Rhodes identifies at least three aspects of the
field that she believes require significant rethinking and reform (Rhodes 2005). Each is part …

Public health and service delivery programmes, interventions and policies (collectively,'
programmes') are typically developed and implemented for the primary purpose of effecting …

For decades, ethical codes, guidelines and regulations for research involving humans have
held that research must have social value in order to be ethical. The idea was present in the …

Must medical experiments with human subjects offer them a 'favourable risk-benefit ratio',
that is, more expectation of benefit than harm or burden, if they are to be judged as ethically …

Bringing the Common Rule into the 21st Century | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Forty years ago, the Belmont Report counseled that a “systematic, nonarbitrary analysis of
risks and benefits” is vital to ensuring the ethical appropriateness of research with human …

Perhaps the most common, and usually the most important, principle involved in discussions
of research ethics concerns harmful consequences that could result from the actions of …