Child maltreatment and risk for psychopathology in childhood and adulthood

SR Jaffee - Annual review of clinical psychology, 2017 - annualreviews.org
Although rates of child maltreatment are declining, more than 600,000 children in the United
States are substantiated victims of abuse or neglect. The focus of this review is on the …

Scars that won't heal: The neurobiology of child abuse

MH Teicher - Scientific American, 2002 - JSTOR
THE AFTERMATH of childhood abuse can manifest itself at any age in a variety of ways.
Internally it can appear as depression, anxiety, suicidal thoughts or posttraumatic stress; it …

Bringing basic research on early experience and stress neurobiology to bear on preventive interventions for neglected and maltreated children

MR Gunnar, PA Fisher - Development and psychopathology, 2006 - cambridge.org
A major focus in developmental psychopathology is on understanding developmental
mechanisms and, armed with this information, intervening to improve children's outcomes …

Biological alterations affecting risk of adult psychopathology following childhood trauma: a review of sex differences

A Tiwari, A Gonzalez - Clinical Psychology Review, 2018 - Elsevier
Childhood trauma exposure is a significant public health problem. While adult mental health
consequences of such experiences are well documented, sex differences in both …

The impact of childhood maltreatment on biological systems: Implications for clinical interventions

A Gonzalez - Paediatrics & child health, 2013 - academic.oup.com
Childhood maltreatment represents a significant risk factor for the development of a number
of mental and physical health outcomes. Converging evidence suggests that early adversity …

Heightened connectivity between the ventral striatum and medial prefrontal cortex as a biomarker for stress-related psychopathology: understanding interactive effects …

JL Hanson, AR Knodt, BD Brigidi… - Psychological medicine, 2018 - cambridge.org
BackgroundThe experience of childhood maltreatment is a significant risk factor for the
development of depression. This risk is particularly heightened after exposure to additional …

Gene–environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach

V Warrier, ASF Kwong, M Luo, S Dalvie, J Croft… - The Lancet …, 2021 - thelancet.com
Background Childhood maltreatment is associated with poor mental and physical health.
However, the mechanisms of gene–environment correlations and the potential causal …

Practitioner Review: Neurobiological consequences of childhood maltreatment–clinical and therapeutic implications for practitioners

JA Samson, TR Newkirk… - Journal of child …, 2024 - Wiley Online Library
Background Childhood maltreatment is one of the most important preventable risk factors for
a wide variety of psychiatric disorders. Further, when psychiatric disorders emerge in …

Early life stress, the development of aggression and neuroendocrine and neurobiological correlates: what can we learn from animal models?

AH Veenema - Frontiers in neuroendocrinology, 2009 - Elsevier
Early life stress (child and adolescent abuse, neglect and trauma) induces robust alterations
in emotional and social functioning resulting in enhanced risk for the development of …

Neurobiological effects of childhood abuse: implications for the pathophysiology of depression and anxiety

KM Penza, C Heim, CB Nemeroff - Archives of women's mental health, 2003 - Springer
Mood and anxiety disorders are highly prevalent psychiatric disorders, especially in women,
and they are associated with significant morbidity and mortality. A considerable literature …