Classification and mutation prediction from non–small cell lung cancer histopathology images using deep learning

N Coudray, PS Ocampo, T Sakellaropoulos, N Narula… - Nature medicine, 2018 - nature.com
Visual inspection of histopathology slides is one of the main methods used by pathologists
to assess the stage, type and subtype of lung tumors. Adenocarcinoma (LUAD) and …

Classifying non-small cell lung cancer types and transcriptomic subtypes using convolutional neural networks

KH Yu, F Wang, GJ Berry, C Re… - Journal of the …, 2020 - academic.oup.com
Objective Non-small cell lung cancer is a leading cause of cancer death worldwide, and
histopathological evaluation plays the primary role in its diagnosis. However, the …

Deep learning-based six-type classifier for lung cancer and mimics from histopathological whole slide images: a retrospective study

H Yang, L Chen, Z Cheng, M Yang, J Wang, C Lin… - BMC medicine, 2021 - Springer
Background Targeted therapy and immunotherapy put forward higher demands for accurate
lung cancer classification, as well as benign versus malignant disease discrimination. Digital …

Pathologist-level classification of histologic patterns on resected lung adenocarcinoma slides with deep neural networks

JW Wei, LJ Tafe, YA Linnik, LJ Vaickus, N Tomita… - Scientific reports, 2019 - nature.com
Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor
grade and treatment for patients. However, this task is often challenging due to the …

A deep learning model for the classification of indeterminate lung carcinoma in biopsy whole slide images

F Kanavati, G Toyokawa, S Momosaki, H Takeoka… - Scientific reports, 2021 - nature.com
The differentiation between major histological types of lung cancer, such as
adenocarcinoma (ADC), squamous cell carcinoma (SCC), and small-cell lung cancer …

Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features

KH Yu, C Zhang, GJ Berry, RB Altman, C Ré… - Nature …, 2016 - nature.com
Lung cancer is the most prevalent cancer worldwide, and histopathological assessment is
indispensable for its diagnosis. However, human evaluation of pathology slides cannot …

DeepLRHE: a deep convolutional neural network framework to evaluate the risk of lung cancer recurrence and metastasis from histopathology images

Z Wu, L Wang, C Li, Y Cai, Y Liang, X Mo, Q Lu… - Frontiers in …, 2020 - frontiersin.org
It is critical for patients who cannot undergo eradicable surgery to predict the risk of lung
cancer recurrence and metastasis; therefore, the physicians can design the appropriate …

Comparative analysis of machine learning approaches to classify tumor mutation burden in lung adenocarcinoma using histopathology images

A Sadhwani, HW Chang, A Behrooz, T Brown… - Scientific reports, 2021 - nature.com
Both histologic subtypes and tumor mutation burden (TMB) represent important biomarkers
in lung cancer, with implications for patient prognosis and treatment decisions. Typically …

Deep learning for lung cancer detection: tackling the kaggle data science bowl 2017 challenge

K Kuan, M Ravaut, G Manek, H Chen, J Lin… - arXiv preprint arXiv …, 2017 - arxiv.org
We present a deep learning framework for computer-aided lung cancer diagnosis. Our multi-
stage framework detects nodules in 3D lung CAT scans, determines if each nodule is …

A shallow convolutional neural network predicts prognosis of lung cancer patients in multi-institutional computed tomography image datasets

P Mukherjee, M Zhou, E Lee, A Schicht… - Nature machine …, 2020 - nature.com
Lung cancer is the most common fatal malignancy in adults worldwide, and non-small-cell
lung cancer (NSCLC) accounts for 85% of lung cancer diagnoses. Computed tomography is …