The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has resulted in significant morbidity and mortality …

Background COVID-19, a disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), commonly presents as fever, cough, dyspnea, and myalgia or …

The clinical manifestation of moderate to severe coronavirus disease 2019 (COVID-19) has
parallels to secondary hemophagocytic lymphohistiocytosis (HLH) both clinically and based …

Objective Coronavirus disease 2019 (COVID-19) is associated with diffuse lung injury that
can progress to acute respiratory distress syndrome, multisystem-organ failure, and death …

COVID-19 or SARS-CoV-2 infection can lead to severe acute respiratory distress
syndrome/pneumonia with features of cytokine storm reminiscent of secondary …

Cytokine storm is an umbrella term that describes an inflammatory syndrome characterized
by elevated levels of circulating cytokines and hyperactivation of innate and/or adaptive …

Background Secondary hemophagocytic lymphohistiocytosis (sHLH) is a life-threatening
hyperinflammatory event and a fatal complication of viral infections. Whether sHLH may also …

A previously healthy 55-year-old woman presented with fever, malaise, and a mild cough.
Chest radiograph revealed bilateral patchy infiltrates. A nasopharyngeal swab tested …

Interventions: A treatment regimen of methylprednisolone, pentaglobin, and anakinra was
developed and administered. Outcomes: One patient survived the ICU stay. Two other …

Hemophagocytic lymphohistiocytosis (HLH) is a disease that can affect both children and
adults. HLH can be categorized as primary or secondary. Secondary HLH (sHLH) may be …