Natriuretic peptides (NPs) represent a critical pathway in heart failure (HF). We explored
genetic determinants of pharmacodynamic effects of B-type NP (BNP) and changes in …

Background: Natriuretic peptides (NP) represent a critical pathway in heart failure (HF).
However, there is wide individual variability in NP system activity, which is partially genetic …

Abstract Background Natriuretic peptides (NPs) represent a critical pathway in heart failure
(HF). However, there is wide individual variability in NP system activity, which could be partly …

Heart failure (HF) is a modern epidemic and is one of the few cardiovascular diseases which
is increasing in prevalence. The growing importance of the Natriuretic Peptide (NP) system …

The natriuretic peptide (NP) system is a critical physiologic pathway in heart failure with wide
individual variability in functioning. We investigated the genetic component by testing the …

The cardiac natriuretic peptide (NP) system is composed of atrial natriuretic factor (ANF)[1, 2]
and brain natriuretic peptide (BNP)[3]. These polypeptide hormones are synthesized, stored …

Purpose The importance of B-type natriuretic peptide (BNP) as a diagnostic and therapeutic
modality in cardiovascular disease is well known. BNP levels correlate clinical and …

Background: Genetic variants related to the natriuretic peptide (NP) system [Sca I mutated
allele (A1) of the atrial NP (ANP) gene and the C variant of the natriuretic peptide clearance …

The discovery of the heart as an endocrine organ resulted in a remarkable recognition of the
natriuretic peptide system (NPS). Specifically, research has established the production of …

Background: Human genetic variation in the NPR1 (natriuretic peptide receptor 1 gene,
encoding NPR-A, atrial natriuretic peptide receptor 1) was recently shown to affect blood …