Mathematical modeling of interaction between innate and adaptive immune responses in COVID‐19 and implications for viral pathogenesis

SQ Du, W Yuan - Journal of medical virology, 2020 - Wiley Online Library
We have applied mathematical modeling to investigate the infections of the ongoing
coronavirus disease‐2019 (COVID‐19) pandemic caused by SARS‐CoV‐2 virus. We first …

The role of dysregulated immune responses in COVID-19 pathogenesis

S Tahaghoghi-Hajghorbani, P Zafari, E Masoumi… - Virus research, 2020 - Elsevier
Abstract The coronavirus disease-2019 (COVID-19) which caused by severe acute
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …

[HTML][HTML] From infection to immunity: understanding the response to SARS-CoV2 through in-silico modeling

F Castiglione, D Deb, AP Srivastava, P Liò… - Frontiers in …, 2021 - frontiersin.org
Background Immune system conditions of the patient is a key factor in COVID-19 infection
survival. A growing number of studies have focused on immunological determinants to …

Modeling the viral dynamics of SARS-CoV-2 infection

S Wang, Y Pan, Q Wang, H Miao, AN Brown… - Mathematical …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the
infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading …

In-host mathematical modelling of COVID-19 in humans

EA Hernandez-Vargas, JX Velasco-Hernandez - Annual reviews in control, 2020 - Elsevier
COVID-19 pandemic has underlined the impact of emergent pathogens as a major threat to
human health. The development of quantitative approaches to advance comprehension of …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

[PDF][PDF] Mathematical modelling of COVID-19 disease dynamics: Interaction between immune system and SARS-CoV-2 within host

S Chowdhury, JT Chowdhury, SF Ahmed… - AIMS …, 2022 - researchgate.net
SARS-COV-2 (Coronavirus) viral growth kinetics within-host become a key fact to
understand the COVID-19 disease progression and disease severity since the year 2020 …

Therapeutic approaches for COVID-19 based on the dynamics of interferon-mediated immune responses

P Mosaddeghi, M Negahdaripour, Z Dehghani… - 2020 - preprints.org
As the outbreak of COVID-19 has accelerated, an urgent need for finding strategies to
combat the virus is growing. Thus, gaining more knowledge on the pathogenicity …

Within host dynamics of SARS-CoV-2 in humans: Modeling immune responses and antiviral treatments

I Ghosh - SN Computer Science, 2021 - Springer
In December 2019, a newly discovered SARS-CoV-2 virus was emerged from China and
propagated worldwide as a pandemic, resulting in about 3–5% mortality. Mathematical …

Innate immunity plays a key role in controlling viral load in COVID-19: mechanistic insights from a whole-body infection dynamics model

P Dogra, J Ruiz-Ramírez, K Sinha… - ACS pharmacology & …, 2020 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a pathogen of immense
public health concern. Efforts to control the disease have only proven mildly successful, and …