SARS-CoV-2 genetic variations associated with COVID-19 pathogenicity

P Aiewsakun, P Nilplub… - Microbial …, 2021 - microbiologyresearch.org
In this study, we performed genome-wide association analyses on SARS-CoV-2 genomes to
identify genetic mutations associated with pre-symptomatic/asymptomatic COVID-19 cases …

Role of genomics in combating COVID-19 pandemic

KA Saravanan, M Panigrahi, H Kumar, D Rajawat… - Gene, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) quickly swept over the world, becoming
one of the most devastating outbreaks in human history. Being the first pandemic in the post …

Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects

GHL Roberts, R Partha, B Rhead, SC Knight, DS Park… - Nature Genetics, 2022 - nature.com
Multiple COVID-19 genome-wide association studies (GWASs) have identified reproducible
genetic associations indicating that there is a genetic component to susceptibility and …

[HTML][HTML] Novel and emerging mutations of SARS-CoV-2: Biomedical implications

E Mohammadi, F Shafiee, K Shahzamani… - Biomedicine & …, 2021 - Elsevier
Abstract Coronavirus disease-19 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 virus strains has geographical …

[HTML][HTML] Genetic variation in SARS-CoV-2 may explain variable severity of COVID-19

SK Biswas, SR Mudi - Medical hypotheses, 2020 - ncbi.nlm.nih.gov
The coronavirus disease 2019 (COVID-19) is highly contagious and is rapidly spreading all
over the world. Although the majority of the COVID-19 patients are either asymptomatic or …

Detailed stratified GWAS analysis for severe COVID-19 in four European populations

F Degenhardt, D Ellinghaus, S Juzenas… - Human molecular …, 2022 - academic.oup.com
Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a
deeper analysis of the host genetic contribution to severe COVID-19 is important to improve …

Host genetic variants potentially associated with SARS-CoV-2: a multi-population analysis

MK Smatti, YA Al-Sarraj, O Albagha… - Frontiers in genetics, 2020 - frontiersin.org
Background Clinical outcomes of coronavirus disease 2019 (COVID-19), caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) showed enormous inter …

COVID-19: Time for precision epidemiology

S Koks, RW Williams, J Quinn… - Experimental …, 2020 - journals.sagepub.com
The global COVID-19 (SARS-CoV2, COVID-19) tsunami caused by SARSCoV2 is
inundating and often-overwhelming health care systems in most countries and regions …

Mapping the human genetic architecture of COVID-19

Writing group Writing group leaders Pathak Gita A. 6 … - Nature, 2021 - nature.com
The genetic make-up of an individual contributes to the susceptibility and response to viral
infection. Although environmental, clinical and social factors have a role in the chance of …

[HTML][HTML] Genetic risk of severe Covid-19

A Kaser - New England Journal of Medicine, 2020 - Mass Medical Soc
The large majority of patients infected with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have mild or no symptoms, 1 whereas a small proportion of patients have …