Abstract Arsenic (+ 3 oxidation state) methyltransferase (As3mt) catalyzes methylation of
inorganic arsenic (iAs) producing a number of methylated arsenic metabolites. Although …

Arsenic methyltransferase (As3mt) catalyzes the conversion of inorganic arsenic (iAs) to its
methylated metabolites, including toxic methylarsonite (MAs III) and dimethylarsinite (DMAs …

Abstract Arsenic (+ 3 oxidation state) methyltransferase (As3mt) is the key enzyme in the
pathway for methylation of inorganic arsenic (iAs). Altered As3mt expression and AS3MT …

Arsenic (+ 3 oxidation state) methyltransferase (As3mt) catalyzes formation of mono-, di-,
and tri-methylated metabolites of inorganic arsenic. Distribution and retention of arsenic …

Abstract Arsenic (+ 3 oxidation state) methyltransferase (As3mt) plays a central role in the
enzymatically catalyzed conversion of inorganic arsenic into methylated metabolites. Most …

The arsenic (+ 3 oxidation state) methyltransferase (As3mt) gene encodes a 43 kDa protein
that catalyzes methylation of inorganic arsenic. Altered expression of AS3MT in cultured …

The metabolism of arsenicals, including their reduction and methylation has been
extensively studied, and both classical and novel pathways of arsenic methylation are …

Recent studies have suggested that polymorphisms in the methylation of inorganic arsenic
(iAs) exist in animals and humans. Methylation of iAs is an important step in the elimination …

Inorganic arsenic is enzymatically methylated; hence, its ingestion results in exposure to the
parent compound and various methylated arsenicals. Both experimental and …

Inorganic arsenic (iAs) exposure has been associated with the increased risk of various
forms of cancer and of non-cancerous diseases. Metabolic conversions of iAs that yield …