A highly virulent variant of HIV-1 circulating in the Netherlands

C Wymant, D Bezemer, F Blanquart, L Ferretti, A Gall… - Science, 2022 - science.org
We discovered a highly virulent variant of subtype-B HIV-1 in the Netherlands. One hundred
nine individuals with this variant had a 0.54 to 0.74 log10 increase (ie, a~ 3.5-fold to 5.5-fold …

HIV-1 nomenclature proposal

DL Robertson, JP Anderson, JA Bradac, JK Carr… - Science, 2000 - science.org
A clear and consistent genetic classification of human immunodeficiency virus-type 1 (HIV-1)
strains continues to be of great utility in epidemiological tracking of the AIDS pandemic and …

HIV-1 evolution and disease progression

MA Nowak, RM Anderson, MC Boerlijst, S Bonhoeffer… - Science, 1996 - science.org
1 008 the two patients who progressed rapidly to disease had low genetic diversity. The
statement that such findings refute our theory rests on the incorrect assumption that the …

Extensive variation of human immunodeficiency virus type-1 in vivo

MS Saag, BH Hahn, J Gibbons, Y Li, ES Parks… - Nature, 1988 - nature.com
Genotypic variation among independent isolates of human immunodeficiency virus type-1
(HIV-1) is well known1–9, but its molecular basis and biological consequences are poorly …

Genotypic and phenotypic characterization of HIV-1 patients with primary infection

T Zhu, H Mo, N Wang, DS Nam, Y Cao, RA Koup… - Science, 1993 - science.org
Better characterization of human immunodeficiency virus-type 1 (HIV-1) in patients with
primary infection has important implications for the development of an acquired …

Biologically diverse molecular variants within a single HIV-1 isolate

AG Fisher, B Ensoli, D Looney, A Rose, RC Gallo… - Nature, 1988 - nature.com
AIDS is a disorder characterized by a slow progressive impairment of immune function and
by infection of human immunodeficiency viruses (HIV-1, HIV-2) 1–4. Our knowledge of how …

An African HIV-1 sequence from 1959 and implications for the origin of the epidemic

T Zhu, BT Korber, AJ Nahmias, E Hooper, PM Sharp… - Nature, 1998 - nature.com
There is considerable genetic diversity among viruses of different subtypes (designated A to
J) in the major group of human immunodeficiency virus type 1 (HIV-1), the form of HIV that is …

Biologic features of HIV-1 that correlate with virulence in the host

C Cheng-Mayer, D Seto, M Tateno, JA Levy - Science, 1988 - science.org
Individuals infected with the human immunodeficiency virus type 1 (HIV-1) may be
asymptomatic or have AIDS-related complex or the acquired immuno deficiency syndrome …

25 years of HIV

AS Fauci - Nature, 2008 - nature.com
25 years of HIV | Nature Skip to main content Thank you for visiting nature.com. You are using
a browser version with limited support for CSS. To obtain the best experience, we recommend …

Detection of diverse HIV-1 genetic subtypes in the USA

SK Brodine, FC Garland, JR Mascola, KR Porter… - The Lancet, 1995 - thelancet.com
Of the nine genetic subtypes of HIV-1 that exist world wide, subtype B predominates in North
America and Europe. Thus, most knowledge about HIV-1 and most vaccine development …