Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell

J Li, LL Deng, ZY Zhou, D Yuan… - Zhongguo Zhong yao …, 2017 - europepmc.org
To investigate the protective effect of Panax notoginseng saponins combined with total
flavonoids of epimedium on D-gal-induced senescence of H9c2 cells and explore its …

Study on protective effect of Panax notoginseng total saponins on H9c2 cells senescence against D-galactose

J Li, L Yang, JZ Wang, CC Zhang, T Wang… - Zhong yao cai …, 2014 - europepmc.org
Objective To investigate the protective effect of Panax notoginseng Total Saponins (PNTS)
on D-galactose-induced H9c2 cell senescence and the underlying mechanism. Methods D …

Experimental studies on anti-aging actions of total Saponins of Radix Notoginseng

Z QU, Z XIE, N WANG, Y PAO… - Journal of Guangzhou …, 1999 - pesquisa.bvsalud.org
[Objective] To observe the anti-aging actions of total saponins of Radix Notoginseng, ie,
Panax Notoginseng saponins (PNS) on rats with Alzheimer's Disease (AD).[Methods] …

20 (S)‐protopanaxatriol inhibited D‐galactose‐induced brain aging in mice via promoting mitochondrial autophagy flow

J Zhang, R Hu, K Chen, Y Liu, Y Hou… - Phytotherapy …, 2023 - Wiley Online Library
Previous reports have confirmed that saponins (ginsenosides) derived from Panax ginseng.
CA Meyer exerted obvious memory‐enhancing and antiaging effects, and the simpler the …

Protective Effect of Total Flavonoids of Epimedium on D-galactose-induced Senescence in H9c2 Cells

J Li, CC Zhang, L Yang, T Wang, ZY Zhou… - Zhong yao cai …, 2014 - europepmc.org
Objective To investigate the protective effect of Total Flavonids of Epimedium (TFE) on D-
galactose-induced H9c2 cells senescence and to explore the underlying mechanisms …

Saponins from Panax japonicus improve neuronal mitochondrial injury of aging rats

C Fan, JX Wang, ZE Xiong, SS Hu, AJ Zhou… - Pharmaceutical …, 2023 - Taylor & Francis
Context Panax japonicus is the dried rhizome of Panax japonicus CA Mey.(Araliaceae).
Saponins from Panax japonicus (SPJ) exhibit anti-oxidative and anti-aging effects. Objective …

Evaluating the effects of mitochondrial autophagy flux on ginsenoside Rg2 for delaying D-galactose induced brain aging in mice

J Zhang, K Chen, Y Zhou, H Wei, M Qi, Z Wang… - Phytomedicine, 2022 - Elsevier
Background Aging is an inevitable gradual process of the body, which can cause
dysfunction or degeneration of the nervous or immune system, thus becoming a critical …

Antioxidant Effects of Sophora davidi (Franch.) Skeels on d–Galactose–Induced Aging Model in Mice via Activating the SIRT1/p53 Pathway

B Lin, D Xu, S Wu, S Qi, Y Xu, X Liu, X Zhang… - Frontiers in …, 2021 - frontiersin.org
This study investigated the protective effect of Sophora davidi (Franch.) Skeels fruits extract
(SDE) on d–galactose–induced acute aging in mice. Ultra performance liquid …

Protective mechanism of ginsenoside Rg1 on hippocampus of aging mice induced by D-galactose

Y XIANG - Chinese Traditional and Herbal Drugs, 2017 - pesquisa.bvsalud.org
Objective To investigate the protective mechanism of ginsenoside Rg1 on hippocampus of
aging mice induced by D-galactose. Methods Forty nestin-green fluorescent protein (GFP) …

Effect of ginsenoside Rg1 on expression of p21, cyclin E and CDK2 in the process of cell senescence

CH Zhao, XC Chen, JS Jin, YG Zhu, GB Shi… - Yao xue xue bao …, 2004 - europepmc.org
Aim To explore the possible role of p21, cyclin E and cyclin-dependent kinase 2 (CDK2) in
the protection of ginsenoside Rg1 against tert-butylhydroperoxide (t-BHP)-induced …