Design of multi-epitope vaccine candidate based on OmpA, CarO and ZnuD proteins against multi-drug resistant Acinetobacter baumannii

B Negahdari, P Sarkoohi, B Shahbazi, K Ahmadi - Heliyon, 2024 - cell.com
Acinetobacter baumannii has been identified as a major cause of nosocomial infections.
Acinetobacter infections are often difficult to treat with multidrug resistant phenotypes. One of …

Prioritization of potential vaccine targets using comparative proteomics and designing of the chimeric multi-epitope vaccine against Pseudomonas aeruginosa

V Solanki, M Tiwari, V Tiwari - Scientific reports, 2019 - nature.com
Multidrug-resistant Pseudomonas aeruginosa is one of the worldwide health problems
involved in elevated mortality and morbidity. Therefore, it is important to find a therapeutic for …

A subunit vaccine against pneumonia: targeting Streptococcus pneumoniae and Klebsiella pneumoniae

MO Rafi, K Al-Khafaji, SM Mandal, NS Meghla… - … Modeling Analysis in …, 2023 - Springer
Community-acquired pneumonia is primarily caused by Streptococcus pneumoniae and
Klebsiella pneumoniae, two pathogens that have high morbidity and mortality rates. This is …

Multi epitope vaccine candidate design against Streptococcus pneumonia

Y Devarakonda, MVNJ Reddy, RS Neethu… - Journal of …, 2023 - Taylor & Francis
Streptococcus pneumonia, the causative agent of sepsis, meningitis and pneumonia, is held
responsible for causing invasive diseases predominantly in children along with adults from …

[PDF][PDF] Immunoinformatics Approaches for Developing Multi-Epitope Subunit Vaccines to Combat Acinetobacter Baumannii

P Pan, F Zhu, S Ma, M Rao, P Zhang, W Peng, Y Cui… - 2022 - scholar.archive.org
Acinetobacter baumannii, a Gram-negative opportunistic pathogen that widely exists in the
environment, causes numerous nosocomial infection cases in the ICU. As the agent of …

Genome-Based Multi-Antigenic Epitopes Vaccine Construct Designing against Staphylococcus hominis Using Reverse Vaccinology and Biophysical Approaches

M Nawaz, A Ullah, AI Al-Harbi, MU Haq, AR Hameed… - Vaccines, 2022 - mdpi.com
Staphylococcus hominis is a Gram-positive bacterium from the staphylococcus genus; it is
also a member of coagulase-negative staphylococci because of its opportunistic nature and …

In silico design of an epitope-based vaccine against PspC in Streptococcus pneumoniae using reverse vaccinology

M Nahian, M Shahab, L Mazumder, JIN Oliveira… - Journal of Genetic …, 2023 - Elsevier
Background Streptococcus pneumoniae is a major pathogen that poses a significant hazard
to global health, causing a variety of infections including pneumonia, meningitis, and sepsis …

Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches

J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …

Klebsiella pneumoniae vaccine studies in animal models

P Ranjbarian, ZS Amjad, RC Lorestani, A Shojaeian… - Biologicals, 2023 - Elsevier
The treatment of Klebsiella pneumoniae is faced with challenges demanding the
development of a vaccination strategy. However, no approved and globally available …

B Cell Epitopes of Four Fimbriae Antigens of Klebsiella pneumoniae: A Comprehensive In Silico Study for Vaccine Development

FN Zargaran, A Akya, S Rezaeian, K Ghadiri… - International journal of …, 2021 - Springer
Klebsiella pneumoniae is one of the major causes of nosocomial infections worldwide which
can cause several diseases in children and adults. The globally dissemination of hyper …