Fracture healing is a complex physiological process. Local vascularity at the site of the
fracture has been established as one of the most important factors influencing the healing …

Stem cells of various origins, particularly endothelial progenitor cells (EPCs), have potential
to enhance bone repair and regeneration. EPCs are resident in the bone marrow and home …

Early vascularization of a composite in a critical bone defect is a prerequisite for ingrowth of
osteogenic reparative cells to regenerate bone, since lack of vessels does not ensure a …

Inadequate blood supply frequently impedes the viability of tissue-engineered constructs in
the initial phase after implantation, and can lead to improper cell integration or cell death …

Bone regeneration is a complex, well-orchestrated process based on the interactions
between osteogenesis and angiogenesis, observed in both physiological and pathological …

Association of the bone‐forming osteoblasts (OBs) and vascular endothelial cells (ECs) into
a biomaterial composite provides a live bone graft substitute that can repair the bone defect …

Purpose Treating fracture nonunion with endothelial progenitor cells (EPCs) is a promising
approach. Nevertheless, the effect of different EPC-related cell populations remains unclear …

Introduction. Cancellous bone is frequently used for filling bone defects in a clinical setting. It
provides favourable conditions for regenerative cells such as MSC and early EPC. The …

In bone tissue engineering (TE) endothelial cell‐osteoblast cocultures are known to induce
synergies of cell differentiation and activity. Bone marrow mononucleated cells (BMCs) are a …

According to present knowledge, blood derived endothelial progenitor cells (EPC) might act
as proangiogenic myeloid cells, which play a fundamental role in the regulation of …