A genome-wide search identifies potential new susceptibility loci for Crohn's disease

Y Ma, JD Ohmen, Z Li, GL Bentley… - Inflammatory bowel …, 1999 - academic.oup.com
Chronic inflammatory bowel disease (IBD) presents as two major clinical forms, Crohn's
disease (CD) and ulcerative colitis (UC). Genetic epidemiological studies and animal …

[PDF][PDF] Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci

JD Rioux, MS Silverberg, MJ Daly, AH Steinhart… - The American Journal of …, 2000 - cell.com
The chronic inflammatory bowel diseases (IBDs)—Crohn disease (CD) and ulcerative colitis
(UC)—are idiopathic, inflammatory disorders of the gastrointestinal tract. These conditions …

Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: Evidence for epistasis between 1p and IBD1

JH Cho, DL Nicolae, LH Gold… - Proceedings of the …, 1998 - National Acad Sciences
The idiopathic inflammatory bowel diseases, Crohn's disease (CD) and ulcerative colitis
(UC), are chronic, frequently disabling diseases of the intestines. Segregation analyses, twin …

[PDF][PDF] A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort

J Hampe, S Schreiber, SH Shaw, KF Lau… - The American journal of …, 1999 - cell.com
Inflammatory bowel disease (IBD) is characterized by a chronic relapsing intestinal
inflammation, typically starting in early adulthood. IBD is subdivided into two subtypes, on …

[HTML][HTML] Inflammatory bowel disease: genetics, epigenetics, and pathogenesis

I Loddo, C Romano - Frontiers in immunology, 2015 - frontiersin.org
Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders characterized by
chronic relapsing intestinal inflammation. Although etiology remains largely unknown, recent …

The genetics of Crohn's disease and ulcerative colitis – status quo and beyond

D Ellinghaus, J Bethune, BS Petersen… - Scandinavian journal of …, 2015 - Taylor & Francis
The two major subtypes of inflammatory bowel disease (IBD), ulcerative colitis (UC, MIM#
191390) and Crohn's disease (CD, MIM# 266600), are chronic relapsing-remitting …

[PDF][PDF] The IBD2 locus shows linkage heterogeneity between ulcerative colitis and Crohn disease

M Parkes, MM Barmada, J Satsangi, DE Weeks… - The American Journal of …, 2000 - cell.com
The IBD2 locus on chromosome 12 has been linked to both Crohn disease (CD) and
ulcerative colitis (UC) but has not been detected in some CD-dominated data sets. In the …

Replication and extension studies of inflammatory bowel disease susceptibility regions confirm linkage to chromosome 6p (IBD3)

B Dechairo, C Dimon, D van Heel, I Mackay… - European Journal of …, 2001 - nature.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine,
commonly diagnosed as either ulcerative colitis (UC) or Crohn's disease (CD) …

Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16

ME Curran, KF Lau, J Hampe, S Schreiber, S Bridger… - Gastroenterology, 1998 - Elsevier
Background & Aims: Inflammatory bowel disease (IBD) is a complex disorder of unknown
etiology. Epidemiological investigations suggest a genetic basis for IBD. Recent genetic …

The IBD international genetics consortium provides further evidence for linkage to IBD4 and shows gene-environment interaction

M Pierik, H Yang, MM Barmada… - Inflammatory bowel …, 2005 - academic.oup.com
Abstract Background and Aims The inflammatory bowel diseases (IBDs) Crohn's disease
(CD) and ulcerative colitis are complex disorders with an important genetic determinant. One …