Legionella pneumophila is a ubiquitous Gram-negative bacterium and the causative agent
of Legionnaires' disease and Pontiac fever. The facultative intracellular bacterium colonizes …

The causative agent of Legionnaires' disease, Legionella pneumophila, is an environmental
bacterium, that replicates in macrophages, parasitizes amoeba, and forms biofilms. L …

Highlights•L. pneumophila small molecule signaling comprises the quorum sensing
autoinducer LAI-1 and c-di-GMP.•Legionella quorum sensing and c-di-GMP signaling …

Legionella pneumophila is an opportunistic human pathogen that replicates within
environmental amoebae including Acanthamoeba castellanii and Dictyostelium discoideum …

Legionella species are facultative intracellular pathogens that cause a life-threatening
pneumonia termed Legionnaires' disease. Legionella pneumophila employs the Lqs-LvbR …

Pathogenic bacteria have many strategies for causing disease in humans. One such
strategy is the ability to live both as single-celled motile organisms or as part of a community …

The causative agent of Legionnaires' disease, Legionella pneumophila, colonizes amoebae
and biofilms in the environment. The opportunistic pathogen employs the Lqs (Legionella …

The water‐borne bacterium Legionella pneumophila replicates in environmental protozoa
and upon inhalation destroys alveolar macrophages, thus causing a potentially fatal …

Highlights•Legionella quorum sensing signals through 3-hydroxypentadecane-4-one (LAI-
1).•The Lqs system regulates bacterial virulence, motility and competence.•Synthetic LAI-1 …

Legionellosis is mostly caused by Legionella pneumophila (Lp) and is defined by a severe
respiratory illness with a case fatality rate ranging from 5 to 80%. In a previous study, we …