PSA reduces prostate cancer cell motility by stimulating TRPM8 activity and plasma membrane expression
Although the transient receptor potential melastatin 8 (TRPM8) cold receptor is highly
expressed in prostate cancer (PCa) and constitutes a promising diagnostic and prognostic …
expressed in prostate cancer (PCa) and constitutes a promising diagnostic and prognostic …
TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of prostate cancer cell lines
AI Sagredo, EA Sagredo, V Pola… - Journal of Cellular …, 2019 - Wiley Online Library
Abstract Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca2+‐activated and voltage‐
dependent monovalent cation channel, which depolarizes the plasma cell membrane …
dependent monovalent cation channel, which depolarizes the plasma cell membrane …
Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators
B Beck, G Bidaux, A Bavencoffe, L Lemonnier… - Cell calcium, 2007 - Elsevier
One of the best-studied temperature-gated channels is transient receptor potential
melastatin 8 (TRPM8), which is activated by cold and cooling agents, such as menthol …
melastatin 8 (TRPM8), which is activated by cold and cooling agents, such as menthol …
Menthol inhibits the proliferation and motility of prostate cancer DU145 cells
Y Wang, X Wang, Z Yang, G Zhu, D Chen… - Pathology & Oncology …, 2012 - Springer
In recent years, the transient receptor potential melastatin member 8 (TRPM8) channel has
emerged as a promising prognostic marker and putative therapeutic target in prostate …
emerged as a promising prognostic marker and putative therapeutic target in prostate …
[HTML][HTML] Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function
In recent years, the transient receptor potential melastatin member 8 (TRPM8) channel has
emerged as a promising prognostic marker and putative therapeutic target in prostate …
emerged as a promising prognostic marker and putative therapeutic target in prostate …
Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human …
Recent cloning of a cold/menthol-sensitive TRPM8 channel (transient receptor potential
melastatine family member 8) from rodent sensory neurons has provided the molecular …
melastatine family member 8) from rodent sensory neurons has provided the molecular …
TRPM8 puts the chill on prostate cancer
GP Grolez, D Gkika - Pharmaceuticals, 2016 - mdpi.com
Prostate cancer (PCa) is one of the most frequently diagnosed cancers in developed
countries. Several studies suggest that variations in calcium homeostasis are involved in …
countries. Several studies suggest that variations in calcium homeostasis are involved in …
[HTML][HTML] Small molecular inhibitors block TRPM4 currents in prostate cancer cells, with limited impact on cancer hallmark functions
A Borgstroem, B Hauert, S Kappel, E Zoni… - Journal of molecular …, 2021 - Elsevier
Transient receptor potential melastatin 4 (TRPM4) is a broadly expressed Ca 2+ activated
monovalent cation channel that contributes to the pathophysiology of several diseases. For …
monovalent cation channel that contributes to the pathophysiology of several diseases. For …
TRPM8 ion channels as potential cancer biomarker and target in pancreatic cancer
NS Yee - Advances in protein chemistry and structural biology, 2016 - Elsevier
This article provides a review and discussion of the transient receptor potential melastatin-
subfamily member 8 (TRPM8) ion channel as a potential biomarker and target in cancer …
subfamily member 8 (TRPM8) ion channel as a potential biomarker and target in cancer …
[HTML][HTML] Effects of TRPM8 on the proliferation and motility of prostate cancer PC-3 cells
ZH Yang, XH Wang, HP Wang, LQ Hu - Asian journal of andrology, 2009 - ncbi.nlm.nih.gov
We investigated the effects of transient receptor potential M8 (TRPM8) channel on the
proliferation and motility of androgen-independent prostate cancer PC-3 cells. After being …
proliferation and motility of androgen-independent prostate cancer PC-3 cells. After being …