A multidimensional neural maturation index reveals reproducible developmental patterns in children and adolescents

M Truelove-Hill, G Erus, V Bashyam… - Journal of …, 2020 - Soc Neuroscience
Adolescence is a time of extensive neural restructuring, leaving one susceptible to atypical
development. Although neural maturation in humans can be measured using functional and …

Brain maturation: predicting individual BrainAGE in children and adolescents using structural MRI

K Franke, E Luders, A May, M Wilke, C Gaser - Neuroimage, 2012 - Elsevier
BACKGROUND: Neural development during human childhood and adolescence involves
highly coordinated and sequenced events, characterized by both progressive and …

Development and validation of a brain maturation index using longitudinal neuroanatomical scans

B Cao, B Mwangi, KM Hasan, S Selvaraj, CP Zeni… - Neuroimage, 2015 - Elsevier
Background Major psychiatric disorders are increasingly being conceptualized as
'neurodevelopmental', because they are associated with aberrant brain maturation. Several …

[HTML][HTML] Neuroanatomical assessment of biological maturity

TT Brown, JM Kuperman, Y Chung, M Erhart… - Current biology, 2012 - cell.com
Structural MRI allows unparalleled in vivo study of the anatomy of the developing human
brain. For more than two decades [1], MRI research has revealed many new aspects of this …

Estimating the age of healthy infants from quantitative myelin water fraction maps

DC Dean III, J O'Muircheartaigh, H Dirks… - Human brain …, 2015 - Wiley Online Library
The trajectory of the developing brain is characterized by a sequence of complex, nonlinear
patterns that occur at systematic stages of maturation. Although significant prior …

[HTML][HTML] Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms

MJ Lund, D Alnæs, AMG de Lange, OA Andreassen… - NeuroImage: Clinical, 2022 - Elsevier
Objective Magnetic resonance imaging (MRI) has shown that estimated brain age is deviant
from chronological age in various common brain disorders. Brain age estimation could be …

Prediction of brain maturity in infants using machine-learning algorithms

CD Smyser, NUF Dosenbach, TA Smyser, AZ Snyder… - NeuroImage, 2016 - Elsevier
Recent resting-state functional MRI investigations have demonstrated that much of the large-
scale functional network architecture supporting motor, sensory and cognitive functions in …

[HTML][HTML] Linking brain maturation and puberty during early adolescence using longitudinal brain age prediction in the ABCD cohort

MC Holm, EH Leonardsen, D Beck, A Dahl… - Developmental …, 2023 - Elsevier
The temporal characteristics of adolescent neurodevelopment are shaped by a complex
interplay of genetic, biological, and environmental factors. Using a large longitudinal dataset …

BrainAGE as a measure of maturation during early adolescence

LB Whitmore, SJ Weston, KL Mills - Imaging Neuroscience, 2023 - direct.mit.edu
Abstract The Brain-Age Gap Estimation (BrainAGE) is an important new tool that purports to
evaluate brain maturity when used in adolescent populations. However, it is unclear whether …

[HTML][HTML] Individual variation underlying brain age estimates in typical development

G Ball, CE Kelly, R Beare, ML Seal - Neuroimage, 2021 - Elsevier
Typical brain development follows a protracted trajectory throughout childhood and
adolescence. Deviations from typical growth trajectories have been implicated in …