SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

Key questions in COVID-19 are the duration and determinants of infectious virus shedding.
Here, we report that infectious virus shedding is detected by virus cultures in 23 of the 129 …

The dynamics of SARS-CoV-2 replication and shedding in humans remain poorly
understood. We captured the dynamics of infectious virus and viral RNA shedding during …

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
infected over four million people worldwide. There are multiple reports of prolonged viral …

Objectives Asymptomatic patients, together with those with mild symptoms of coronavirus
disease 2019 (COVID-19), may play an important role in severe acute respiratory syndrome …

SARS-CoV-2 is a human pathogen that causes infection in both the upper respiratory tract
(URT) and the lower respiratory tract (LRT). The viral kinetics of SARS-CoV-2 infection and …

Background Long-term shedding of viral RNA in COVID-19 prevents timely discharge from
the hospital or de-escalation of infection prevention and control practices. Key questions are …

Objective: Transmission of SARS-CoV-2 has significant implications for hospital infection
prevention and control, discharge management, and public health. We reviewed available …

The spread of a novel pathogenic infectious agent eliciting protective immunity is typically
characterised by three distinct phases:(I) an initial phase of slow accumulation of new …

Objectives To summarise the evidence on the detection pattern and viral load of SARS-CoV-
2 over the course of an infection (including any asymptomatic or pre-symptomatic phase) …