Plasmepsin II is a key enzyme in the life cycle of the Plasmodium falciparum parasite
responsible for malaria, a disease that is causing deaths on a worldwide scale. Recently …

Malaria is a life-threatening disease caused by Plasmodium parasites, which are transmitted
to humans through infected female Anopheles mosquitoes. Over the past few decades …

Plasmodium falciparum is the leading cause of malaria with 627,000 deaths annually.
Invasion and egress are critical stages for successful infection of the host yet depend on …

In the present study, we have explored the anti-malarial potential of epoxyazadiradione, the
natural entity extracted from the neem seed oil and its chemical derivatives, against …

Cerebral malaria is a serious and sometimes fatal disease caused by a Plasmodium
falciparum parasite that infects a female anopheles mosquito which feeds on humans. The …

Malaria is an endemic disease caused by the protozoan parasite Plasomodium falciparum.
Febrifugine analogues are natural compound obtained from the traditional Chinese herbs …

Malaria chemotherapy is greatly threatened by the recent emergence and spread of
resistance in the Plasmodium falciparum parasite against artemisinins and their partner …

Falcipain-2 (FP-2) and falcipain-3 (FP-3), haemoglobin-degrading enzymes in Plasmodium
falciparum, are validated drug targets for the development of effective inhibitors against …

This work presents the development of quantitative structure activity relationship (QSAR)
model to predict the antimalarial activity of artemisinin derivatives. The structures of the …

Malaria parasites show resistance to most of the antimalarial drugs and hence developing
antimalarials which can act on multitargets rather than a single target will be a promising …