Cynomolgus macaques have been widely used as an animal model in preclinical
biomedical research and are becoming more popular among HIV/SIV vaccine researchers …

Cytomegalovirus (CMV) is a highly species-specific virus that has co-evolved with its host
over millions of years and thus restricting cross-species infection. To examine the extent to …

Cytomegalovirus (CMV) infection is the most common opportunistic infection in
immunosuppressed individuals, such as transplant recipients or people living with HIV/AIDS …

Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict
species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal …

Background Cytomegaloviruses belong to a large, ancient, genus of DNA viruses comprised
of a wide array of species-specific strains that occur in diverse array of hosts. Methods In this …

Cytomegalovirus (CMV) has been isolated from many nonhuman primates, including rhesus
macaques (Macaca mulatta). To better understand the molecular biology of rhesus CMV …

Highlights•Nonhuman primate (NHP) CMVs are most closely related to human CMV
(HCMV).•Rhesus CMV (RhCMV) bears numerous genomic and functional similarities to …

Cytomegaloviruses (CMV) are highly species-specific due to millennia of co-evolution and
adaptation to their host, with no successful experimental cross-species infection in primates …

Rhesus cytomegalovirus (RhCMV) infection of rhesus macaques is an important model to
investigate critical issues of cytomegalovirus biology. To better understand host …

Studies were initiated to determine whether rhesus cytomegalovirus (RhCMV)-infected
macaques could serve as an animal model for evaluating anti-CMV compounds, as …