The term 'sepsis' can be referred to as the dysfunction of organ (s) because of dysregulated
and uncontrolled response of the host to that particular infection. As per statistics, more than …

Infectious diseases are a major cause of death worldwide. A serious complication of
infections is septic shock. Septic shock is a critical syndrome associated with the host …

The increasing insight into pathomechanisms of dysregulated host response in several
inflammatory diseases led to the implementation of the term “cytokine storm” in the literature …

Several randomized, placebocontrolled clini cal trials (RCTs) have been conducted over the
last 20 years enrolling more than 15,000 patients in total to evaluate the survival benefit …

Sepsis is associated with an exacerbated production of both pro-and anti-inflammatory
cytokines, which are detectable within the bloodstream. Their'half-angel, half-devil'properties …

Background: Sepsis, a systemic inflammatory response to infection, resulting in organ failure
and death. Pathogenic microbial agents trigger cascades of events in sepsis by stimulating …

Severe sepsis and septic shock represent challenging problems for the health care system.
Despite adequate antibiotics and modern intensive care, severe sepsis is associated with a …

Background: Sepsis is a deadly immunological disorder and its pathophysiology is still
poorly understood. We aimed to determine if specific pro-inflammatory and anti-inflammatory …

Sepsis remains a critical problem in virtually all fields of clinical medicine. Despite intensive
scientific and clinical efforts no significant progress has emerged in the fight against sepsis …

Sepsis–the most common cause of death in hospitalized patients–affects over 18 million
people worldwide and has an expected 1% increase of incidence per year. Recent clinical …