Year in review 2013: Critical Care – sepsis

E de Montmollin, D Annane - Critical Care, 2014 - Springer
This review presents key publications from the research field of sepsis published in Critical
Care and other relevant journals during 2013. The results of these experimental studies and …

Sepsis and septic shock

NF Hanna - Advanced Emergency Nursing Journal, 2003 - journals.lww.com
Sepsis or septic shock is the fourth leading cause of long-stay intensive care admissions.
Death may occur despite antimicrobial therapy. The incidence of mortality from sepsis has …

Anti-inflammatory therapies in sepsis and septic shock

BD Freeman, C Natanson - Expert opinion on investigational drugs, 2000 - Taylor & Francis
Despite advances in supportive care, the morbidity and mortality rate resulting from sepsis
and septic shock remain high (30-50%). A central hypothesis driving sepsis research in …

Emerging drugs for the treatment of sepsis

N Heming, L Lamothe, X Ambrosi… - Expert Opinion on …, 2016 - Taylor & Francis
Introduction: The incidence of sepsis, the systemic inflammatory response of the host to an
infectious insult, has steadily increased over past decades. This trend is expected to …

[HTML][HTML] Current sepsis therapeutics

JL Vincent - EBioMedicine, 2022 - thelancet.com
Management of the patient with sepsis comprises three key branches: control of the
underlying infection, haemodynamic stabilization, and modulation of the host response …

[PDF][PDF] The pathophysiology of septic shock

R Saha, S Das, R Chatterjee, I Kaur - … journal of pharma and Bio Sciences, 2010 - Citeseer
While writing this review, Microbiologists, in collaboration with Anaesthetists and Intensivists,
have kept in mind the incidence of sepsis and septic shock along with its mortality and …

Improved understanding of the pathophysiology of sepsis: Setting the scene for potential novel adjunctive therapies

JM Chausse, L Malekele, F Paruk - Southern African Journal of Critical …, 2018 - ajol.info
The occurrence of sepsis in the critically ill population is a dreaded phenomenon when
taking into consideration the devastating complications associated with the disease. Despite …

New concepts of sepsis and their practical value

J Garau - Clinical microbiology and infection, 1999 - clinicalmicrobiologyandinfection …
In an effort to identify a cohort of patients who might benefit from the early administration of
novel therapies designed to modulate the endogenous host inflammatory response, an …

Clinically-oriented therapies in sepsis: a review

MJ Dubois, JL Vincent - Journal of endotoxin research, 2000 - journals.sagepub.com
Our insight of the sepsis response has evolved to encompass not only the pro-inflammatory
but also an anti-inflammatory reaction following infection. Clinical trials have been designed …

Sepsis immunopathology: perspectives of monitoring and modulation of the immune disturbances

T Skirecki, U Borkowska-Zielińska… - Archivum immunologiae …, 2012 - Springer
Septic syndromes are the main cause of death in the intensive care units and although the
mortality rates is slowly decreasing, the occurrence of the disease has been increasing. The …