Sepsis, defined as an infection accompanied by inflammation, is a complex disease process
wherein the body's response to a pathogen is amplified far beyond the initial site of infection …

Sepsis and septic shock continue to be a major cause of morbidity and mortality. Despite
numerous advances in the supportive care of patients with sepsis, the overall mortality has …

The underlying principles of sepsis therapy have remained unchanged for decades. These
include: prompt institution of antimicrobial agents aimed at the inciting pathogen, source …

To reduce the very high mortality rate due to septic shock, a new clinical entity has been
defined: sepsis syndrome. The aggressive treatment of any sepsis syndrome should prevent …

Sepsis is a complex syndrome resulting from an aberrant host response to infection. A
hallmark of sepsis is the failure of the immune system to restore balance. Despite efforts to …

Sepsis, the most common cause of admission to an intensive care unit (ICU), has had an
increased incidence and prevalence over the last years with a simultaneous decrease in its …

Sepsis and septic shock are the leading causes of death in intensive care units in developed
countries despite recent advances in critical care medicine. Sepsis is the systemic …

Sepsis secondary to bacterial infection remains a significant cause of morbidity and mortality
globally. Recent decades have seen the evolution of international collaborations to improve …

Sepsis is a complex syndrome characterized by simultaneous activation of inflammation and
coagulation in response to microbial insult. These events manifest as systemic inflammatory …

Sepsis is one of the most common deadly diseases. Despite its remarkable incidence, and
despite the progress which has been made in understanding this complex syndrome, for …