Salidroside shows anticonvulsant and neuroprotective effects by activating the Nrf2-ARE pathway in a pentylenetetrazol-kindling epileptic model
Y Wu, Y Wang, Y Wu, T Li, W Wang - Brain Research Bulletin, 2020 - Elsevier
Evidence points towards oxidative stress and neuroinflammation being major processes
associated with brain dysfunction in epilepsy. Salidroside reportedly possesses anti …
associated with brain dysfunction in epilepsy. Salidroside reportedly possesses anti …
Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole‐Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway
Epilepsy is a neurodegenerative brain disorder characterized by recurrent seizure attacks.
Numerous studies have suggested a strong correlation between oxidative stress and …
Numerous studies have suggested a strong correlation between oxidative stress and …
Naringin ameliorates pentylenetetrazol-induced seizures and associated oxidative stress, inflammation, and cognitive impairment in rats: possible mechanisms of …
M Golechha, V Sarangal, J Bhatia, U Chaudhry… - Epilepsy & Behavior, 2014 - Elsevier
Oxidative stress and cognitive impairment are associated with PTZ-induced convulsions.
Naringin is a bioflavonoid present in the grapefruit. It is a potent antioxidant, and we …
Naringin is a bioflavonoid present in the grapefruit. It is a potent antioxidant, and we …
Activation of Nrf2-ARE signal pathway protects the brain from damage induced by epileptic seizure
W Wang, Y Wu, G Zhang, H Fang, H Wang, H Zang… - Brain research, 2014 - Elsevier
Epilepsy remains a major medical problem for which there is no effective treatment.
Oxidative damage plays an important role in epilepsy pathogenesis and may represent a …
Oxidative damage plays an important role in epilepsy pathogenesis and may represent a …
Luteolin rescues pentylenetetrazole-induced cognitive impairment in epileptic rats by reducing oxidative stress and activating PKA/CREB/BDNF signaling
JL Zhen, YN Chang, ZZ Qu, T Fu, JQ Liu, WP Wang - Epilepsy & Behavior, 2016 - Elsevier
Most antiepileptic drugs (AEDs) interfere with cognitive function, and there is therefore an
urgent need for AEDs that are effective but do not have this side effect. Various studies have …
urgent need for AEDs that are effective but do not have this side effect. Various studies have …
Neuroprotective effect of Nrf2 activator dimethyl fumarate, on the hippocampal neurons in chemical kindling model in rat
Background Nuclear factor erythroid-2 related factor 2 (Nrf2) is a transcription factor, which
activates the anti-oxidative stress response pathway. In epilepsy, oxidative stress is one of …
activates the anti-oxidative stress response pathway. In epilepsy, oxidative stress is one of …
Ceftriaxone and selenium mitigate seizures and neuronal injury in pentylenetetrazole-kindled rats: oxidative stress and inflammatory pathway
AM Mohamed, DA Ali, E Kolieb, EZ Abdelaziz - International …, 2023 - Elsevier
Epilepsy is one of the most serious worldwide neurological disorders that lead to the
cognitive-psychosocial insults in recurrent seizures. About one third of the patients are drug …
cognitive-psychosocial insults in recurrent seizures. About one third of the patients are drug …
Anogeissus leiocarpus (DC.) Guill and Perr ameliorates pentylenetetrazole-induced seizure/cognitive impairment in rats via inhibition of oxidative stress
HA Audu, A Ahmed, JV Zirahei, NI Dibal… - Advances in Traditional …, 2023 - Springer
The study investigates the role of Anogeissus leiocarpus methanol stem bark extract (ALSE)
on seizure, oxidative stress and cognitive performance in pentylenetetrazole (PTZ)-induced …
on seizure, oxidative stress and cognitive performance in pentylenetetrazole (PTZ)-induced …
Effect of dimethyl fumarate on neuroinflammation and apoptosis in pentylenetetrazol kindling model in rats
Objective Role of apoptosis and neuroinflammation have been well established in the
pathogenesis of epilepsy. It has been reported that the activation of nuclear factor-erythroid …
pathogenesis of epilepsy. It has been reported that the activation of nuclear factor-erythroid …
The Effects of Quinacrine, Proglumide, and Pentoxifylline on Seizure Activity, Cognitive Deficit, and Oxidative Stress in Rat Lithium‐Pilocarpine Model of Status …
M Ahmad, GM Abu-Taweel… - Oxidative medicine …, 2014 - Wiley Online Library
The present data indicate that status epilepticus (SE) induced in adult rats is associated with
cognitive dysfunctions and cerebral oxidative stress (OS). This has been demonstrated …
cognitive dysfunctions and cerebral oxidative stress (OS). This has been demonstrated …