Sarcopenia, a neurogenic syndrome?

P Kwan - Journal of aging research, 2013 - Wiley Online Library
Sarcopenia is an aging‐associated condition, which is currently characterized by the loss of
muscle mass and muscle strength. However, there is no consensus regarding its …

Skeletal muscle oxidative stress and inflammation in aging: Focus on antioxidant and anti-inflammatory therapy

M Chen, Y Wang, S Deng, Z Lian, K Yu - Frontiers in Cell and …, 2022 - frontiersin.org
With aging, the progressive loss of skeletal muscle will have negative effect on multiple
physiological parameters, such as exercise, respiration, thermoregulation, and metabolic …

Sarcopenia: molecular pathways and potential targets for intervention

J Pascual-Fernández, A Fernández-Montero… - International Journal of …, 2020 - mdpi.com
Aging is associated with sarcopenia. The loss of strength results in decreased muscle mass
and motor function. This process accelerates the progressive muscle deterioration observed …

Role and potential mechanisms of anabolic resistance in sarcopenia

PH Haran, DA Rivas, RA Fielding - Journal of cachexia, sarcopenia and …, 2012 - Springer
There is pressing need to understand the aging process to better cope with its associated
physical and societal costs. The age-related muscle wasting known as sarcopenia is a major …

Sarcopenia: current concepts

R Roubenoff, VA Hughes - The Journals of Gerontology Series …, 2000 - academic.oup.com
Sarcopenia, the loss of muscle mass and strength with age, is becoming recognized as a
major cause of disability and morbidity in the elderly population. Sarcopenia is part of …

Dysregulated homeostatic pathways in sarcopenia among frail older adults

TP Ng, Y Lu, RWM Choo, CTY Tan, MSZ Nyunt… - Aging cell, 2018 - Wiley Online Library
Sarcopenia, a core feature of the physical frailty syndrome, is characterized by multisystem
physiological dysregulation. No study has explored qualitatively the hierarchical network of …

[HTML][HTML] Oxidative stress-mediated senescence in mesenchymal progenitor cells causes the loss of their fibro/adipogenic potential and abrogates myoblast fusion

H Sugihara, N Teramoto, K Yamanouchi… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
Sarcopenia is the age-related loss of skeletal muscle mass and function. Skeletal muscle
comprises diverse progenitor cells, including mesenchymal progenitor cells (MPCs), which …

Chronic inflammation and sarcopenia: A regenerative cell therapy perspective

JK Chhetri, P de Souto Barreto, B Fougère… - Experimental …, 2018 - Elsevier
Sarcopenia is characterized by reduced skeletal muscle mass and strength in older
individuals. It is one of the leading cause of physical limitation in older adults, and …

[HTML][HTML] Sarcopenia: Current treatments and new regenerative therapeutic approaches

JH Lo, T Yiu, MT Ong, WY Lee - Journal of orthopaedic translation, 2020 - Elsevier
Sarcopenia is characterized by loss of muscle and reduction in muscle strength that
contributes to higher mortality rate and increased incidence of fall and hospitalization in the …

[HTML][HTML] Sarcopenia of ageing: functional, structural and biochemical alterations

S Zhong, CN Chen, LV Thompson - Brazilian journal of physical …, 2007 - SciELO Brasil
Aging is associated with a progressive decline of muscle mass, strength, and quality, a
condition described as sarcopenia of aging. Despite the significance of skeletal muscle …