Remdesivir for the treatment of Covid-19

JH Beigel, KM Tomashek, LE Dodd… - … England Journal of …, 2020 - Mass Medical Soc
Background Although several therapeutic agents have been evaluated for the treatment of
coronavirus disease 2019 (Covid-19), no antiviral agents have yet been shown to be …

Remdesivir for the treatment of Covid-19—preliminary report

JH Beigel, KM Tomashek, LE Dodd… - … England Journal of …, 2020 - discovery.ucl.ac.uk
BACKGROUND: Although several therapeutic agents have been evaluated for the treatment
of coronavirus disease 2019 (Covid-19), no antiviral agents have yet been shown to be …

Remdesivir for 5 or 10 days in patients with severe Covid-19

JD Goldman, DCB Lye, DS Hui, KM Marks… - … England Journal of …, 2020 - Mass Medical Soc
Background Remdesivir is an RNA polymerase inhibitor with potent antiviral activity in vitro
and efficacy in animal models of coronavirus disease 2019 (Covid-19). Methods We …

Efficacy and harms of remdesivir for the treatment of COVID-19: A systematic review and meta-analysis

A Piscoya, LF Ng-Sueng, A Parra del Riego… - PloS one, 2020 - journals.plos.org
Background Efficacy and safety of treatments for hospitalized COVID-19 are uncertain. We
systematically reviewed efficacy and safety of remdesivir for the treatment of COVID-19 …

Remdesivir for severe coronavirus disease 2019 (COVID-19) versus a cohort receiving standard of care

SA Olender, KK Perez, AS Go, B Balani… - Clinical Infectious …, 2021 - academic.oup.com
Background We compared the efficacy of the antiviral agent, remdesivir, versus standard-of-
care treatment in adults with severe coronavirus disease 2019 (COVID-19) using data from a …

Clinical efficacy and safety of remdesivir in patients with COVID-19: a systematic review and network meta-analysis of randomized controlled trials

CC Lai, CH Chen, CY Wang, KH Chen… - Journal of …, 2021 - academic.oup.com
Objectives We performed a systematic review and network meta-analysis of randomized
controlled trials (RCTs) to provide updated information regarding the clinical efficacy of …

[HTML][HTML] Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial

Y Wang, D Zhang, G Du, R Du, J Zhao, Y Jin, S Fu… - The lancet, 2020 - thelancet.com
Background No specific antiviral drug has been proven effective for treatment of patients
with severe coronavirus disease 2019 (COVID-19). Remdesivir (GS-5734), a nucleoside …

[HTML][HTML] Effect of remdesivir vs standard care on clinical status at 11 days in patients with moderate COVID-19: a randomized clinical trial

CD Spinner, RL Gottlieb, GJ Criner, JRA López… - Jama, 2020 - jamanetwork.com
Importance Remdesivir demonstrated clinical benefit in a placebo-controlled trial in patients
with severe coronavirus disease 2019 (COVID-19), but its effect in patients with moderate …

Remdesivir for coronavirus disease 2019 (COVID-19): a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials

GN Okoli, R Rabbani, L Copstein, A Al-Juboori… - Infectious …, 2021 - Taylor & Francis
Background In view of many unanswered clinical questions regarding treatment of COVID-
19 with remdesivir, we systematically identified, critically appraised and summarized the …

Efficacy and safety of remdesivir in hospitalized Covid‐19 patients: systematic review and meta‐analysis including network meta‐analysis

HK Elsawah, MA Elsokary, MS Abdallah… - Reviews in medical …, 2021 - Wiley Online Library
Remdesivir is an antiviral agent that has shown broad‐spectrum activity, including against
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Clinical trials investigating …