For over a century, psychiatric disorders have been defined by expert opinion and clinical
observation. The modern DSM has relied on a consensus of experts to define categorical …

Psychiatric genetics has taught us a great deal about the nature of psychiatric disorders.
Traditional family, twin and adoption studies have demonstrated the substantial role of …

Failure to obtain convincing results in psychiatric genetics can partly be attributed to the fact
that progress in molecular biology and genetic epidemiology has not been followed by an …

Recent findings in psychiatric genetics have crystallized concerns that diagnostic categories
used in the clinic map poorly onto the underlying biology. If we are to harness developments …

The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of
psychiatry. This global effort is dedicated to rapid progress and open science, and in the …

Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

Over the last decade, genome-wide association studies of psychiatric disorders have
identified numerous significant loci. Whereas these studies initially depended on cohorts …

Genome-wide association studies have identified hundreds of robust genetic associations
underlying psychiatric disorders and provided important biological insights into disease …

Genetic influences play a significant role in risk for psychiatric disorders, prompting
numerous endeavors to further understand their underlying genetic architecture. In this …

Studies of the genetics of psychiatric disorders have become one of the most exciting and
fast-moving areas in human genetics. A decade ago, there were few reproducible findings …