The outbreak of the SARS-CoV-2 virus and its rapid spread into a global pandemic made
the urgent development of scalable vaccines to prevent coronavirus disease (COVID-19) a …

The coronavirus disease 2019 (COVID-19) pandemic, caused by infection with the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is having a deleterious impact on …

A mouse model of SARS-CoV-2 that can be developed in any molecular biology lab with
standard facilities will be valuable in evaluating drugs and vaccines. Here we present a …

Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has led to a global pandemic. New technologies …

The ongoing global pandemic of coronavirus disease 2019 (COVID-19) calls for an urgent
development of effective and safe prophylactic and therapeutic measures. The spike (S) …

The global SARS-CoV-2 pandemic prompted rapid development of COVID-19 vaccines.
Although several vaccines have received emergency approval through various public health …

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection is a global threat. To forestall the …

Despite mass public health efforts, the SARS-CoV2 pandemic continues as of late 2021 with
resurgent case numbers in many parts of the world. The emergence of SARS-CoV2 variants …

Nucleic acid vaccines are designed based on genetic sequences (DNA or mRNA) of a target
antigen to be expressed in vivo to drive a host immune response. In response to the COVID …

Carrier-free naked mRNA vaccines may reduce the reactogenicity associated with delivery
carriers; however, their effectiveness against infectious diseases has been suboptimal. To …