BACKGROUND: Measurement of circulating natriuretic peptides has been shown to play an
important role in diagnosis and prognosis in patients with chronic heart failure. Whether …

The care of patients with heart failure can be challenging, with few objective tools available
to assist in therapy decision-making. Natriuretic peptides are powerfully prognostic …

Background and Purpose: Natriuretic peptides have led the way as a diagnostic and
prognostic tool for the diagnosis and management of heart failure (HF). More recent …

Heart failure is a clinical condition with complex pathophysiology that involves many
different processes. Diagnosis is often difficult in patients presenting for the first time with …

Abstract Objectives: The GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker
Intensified Treatment in Heart Failure) study is designed to determine the safety, efficacy …

PURPOSE: B-type natriuretic peptide is one of the most sensitive and specific biohumoral
markers of heart failure. We hypothesized that B-type natriuretic peptide changes during …

The natriuretic peptides are a family of related hormones that play a crucial role in
cardiovascular homeostasis. They have recently emerged as potentially important clinical …

Heart failure (HF) is a leading cause of morbidity and mortality worldwide. Testing for
natriuretic peptide markers, such as B-type natriuretic peptide (BNP) or N-terminal proBNP …

Importance The natriuretic peptides are biochemical markers of heart failure (HF) severity
and predictors of adverse outcomes. Smaller studies have evaluated adjusting HF therapy …

Januzzi and Troughton Usefulness of NP-Guided Therapy 501 clinician judgment.
Furthermore, to achieve goals of therapy as outlined in guidelines, frequent office visits for …