α-Synuclein is an abundant presynaptic brain protein, misfolding, aggregation and
fibrillation of which are implicated as critical factors in several neurodegenerative diseases …

α-Synuclein belongs to a small group of natively unfolded proteins that can transiently bind
to lipid membranes and acquire a partial α-helical conformation. Under certain pathogenic …

Abstract α-Synuclein is a conserved, abundantly expressed protein that is partially localized
in pre-synaptic terminals in the central nervous system. The precise biological function (s) …

Aggregation of α‐synuclein, an abundant and conserved pre‐synaptic brain protein, is
implicated as a critical factor in several neurodegenerative diseases. These diseases …

α‐Synuclein is an intrinsically unfolded protein that can adopt a partially helical structure
when it interacts with different lipid membranes. Its pathological relevance is linked to its …

α-Synuclein (αsyn) is an abundant brain neuronal protein that can misfold and polymerize to
form toxic fibrils coalescing into pathologic inclusions in neurodegenerative diseases …

The synuclein family of intrinsically unfolded proteins is composed of three highly
homologous members, α-synuclein (αS), β-synuclein (βS) and γ-synuclein (γS), which are …

The synucleins are a family of natively unfolded (or intrinsically unstructured) proteins
consisting of α-, β-, and γ-synuclein involved in neurodegenerative diseases and cancer …

Protein misfolding and aggregation is a ubiquitous phenomenon associated with a wide
range of diseases. The synuclein family comprises three small naturally unfolded proteins …

α-Synuclein (αSN) brain pathology is a conspicuous feature of several neurodegenerative
diseases. These include prevalent conditions such as Parkinson's disease (PD), dementia …