The potential role of IL-6 in monitoring severe case of coronavirus disease 2019

T Liu, J Zhang, Y Yang, H Ma, Z Li, J Zhang, J Cheng… - MedRxiv, 2020 - medrxiv.org
Background The outbreak of coronavirus disease 2019 (COVID-19) in Wuhan City, China
has spreads rapidly since December, 2019. Most patients show mild symptoms, but some of …

The role of interleukin‐6 in monitoring severe case of coronavirus disease 2019

T Liu, J Zhang, Y Yang, H Ma, Z Li, J Zhang… - EMBO molecular …, 2020 - embopress.org
Progression to severe disease is a difficult problem in treating coronavirus disease 2019
(COVID‐19). The purpose of this study is to explore changes in markers of severe disease in …

[HTML][HTML] Longitudinal clinical and radiographic evaluation reveals interleukin-6 as an indicator of persistent pulmonary injury in COVID-19

B Liao, Z Liu, L Tang, L Li, Q Gan, H Shi… - … Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Rationale: Previous studies of coronavirus disease 2019 (COVID-19) were mainly focused
on cross-sectional analysis. In this study, we sought to evaluate the dynamic changes of …

[HTML][HTML] Serum interleukin-6 is an indicator for severity in 901 patients with SARS-CoV-2 infection: a cohort study

J Zhang, Y Hao, W Ou, F Ming, G Liang, Y Qian… - Journal of translational …, 2020 - Springer
Abstract Background Interleukin-6 (IL-6) was proposed to be associated with the severity of
coronavirus disease 2019 (COVID-19). The present study aimed to explore the kinetics of IL …

[HTML][HTML] Interleukine-6 in critically ill COVID-19 patients: A retrospective analysis

J Gorham, A Moreau, F Corazza, L Peluso… - PLoS …, 2020 - journals.plos.org
Introduction Coronavirus disease 2019 (COVID-19) appeared in China in December 2019
and has spread around the world. High Interleukin-6 (IL-6) levels in COVID-19 patients …

[HTML][HTML] Dynamic interleukin-6 level changes as a prognostic indicator in patients with COVID-19

Z Liu, J Li, D Chen, R Gao, W Zeng, S Chen… - Frontiers in …, 2020 - frontiersin.org
Background Interleukin-6 (IL-6), a proinflammatory cytokine, has been reported to be
associated with disease severity and mortality in patients with coronavirus disease 2019 …

Potential factors for prediction of disease severity of COVID-19 patients

H Zhang, X Wang, Z Fu, M Luo, Z Zhang, K Zhang… - MedRxiv, 2020 - medrxiv.org
Abstract Objective Coronavirus disease 2019 (COVID-19) is an escalating global epidemic
caused by SARS-CoV-2, with a high mortality in critical patients. Effective indicators for …

[HTML][HTML] High levels of circulating IL-8 and soluble IL-2R are associated with prolonged illness in patients with severe COVID-19

A Ma, L Zhang, X Ye, J Chen, J Yu, L Zhuang… - Frontiers in …, 2021 - frontiersin.org
Objectives The coordinated immune response of the host is the key of the successful combat
of the body against SARS-CoV-2 infection and is decisive for the development and …

Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study

QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …

Interleukin 6, soluble interleukin 2 receptor alpha (CD25), monocyte colony-stimulating factor, and hepatocyte growth factor linked with systemic hyperinflammation …

L Quartuccio, M Fabris, A Sonaglia, M Peghin… - Cytokine, 2021 - Elsevier
Background Patients infected by SARS-CoV-2 can develop interstitial pneumonia, requiring
hospitalisation or mechanical ventilation. Increased levels of inflammatory biomarkers are …