Selective vulnerability of embryonic cell populations to ethanol‐induced apoptosis: implications for alcohol‐related birth defects and neurodevelopmental disorder
WC Dunty Jr, S Chen, RM Zucker… - Alcoholism: Clinical …, 2001 - Wiley Online Library
Background: Ethanol‐induced cell death has been characterized in very few stages of
embryogenesis. This investigation comprehensively maps patterns of both programmed and …
embryogenesis. This investigation comprehensively maps patterns of both programmed and …
Ethanol‐induced neural crest apoptosis is coincident with their endogenous death, but is mechanistically distinct
MM Cartwright, LL Tessmer… - Alcoholism: Clinical and …, 1998 - Wiley Online Library
The ability of both acute and chronic ethanol exposures to elicit cell death within specific
embryonic and adult tissues is believed to partly underlie ethanol's pathogenicity; however …
embryonic and adult tissues is believed to partly underlie ethanol's pathogenicity; however …
Increased cell death and reduced neural crest cell numbers in ethanol‐exposed embryos: partial basis for the fetal alcohol syndrome phenotype
MM Cartwright, SM Smith - Alcoholism: Clinical and …, 1995 - Wiley Online Library
Fetal alcohol syndrome (FAS) is characterized by growth retardation, craniofacial
malformations, and heart and neural defects; the cellular and molecular mechanism (s) …
malformations, and heart and neural defects; the cellular and molecular mechanism (s) …
Hindbrain and cranial nerve dysmorphogenesis result from acute maternal ethanol administration
WC Dunty Jr, RM Zucker, KK Sulik - Developmental neuroscience, 2002 - karger.com
Acute exposure of mouse embryos to ethanol during stages of hindbrain segmentation
results in excessive cell death in specific cell populations. This study details the ethanol …
results in excessive cell death in specific cell populations. This study details the ethanol …
[HTML][HTML] Alcohol-induced cell death in the embryo
SM Smith - Alcohol health and research world, 1997 - ncbi.nlm.nih.gov
Exposure to alcohol during gestation can have profound consequences, but not all cells
within the embryo are affected equally. Recent advances in molecular embryology have …
within the embryo are affected equally. Recent advances in molecular embryology have …
[引用][C] Fetal alcohol exposure: cellular toxicity and molecular events involved in toxicity
EK Michaelis - Alcoholism: Clinical and Experimental Research, 1990 - Wiley Online Library
RENATAL ETHANOL exposure leads to develop-P mental delays characterized by
decreased growth and differentiation and by visceral and craniofacial malformation. I4 Not …
decreased growth and differentiation and by visceral and craniofacial malformation. I4 Not …
Patterns of ethanol-induced cell death in the developing nervous system of mice; neural fold states through the time of anterior neural tube closure
LE Kotch, KK Sulik - International Journal of Developmental Neuroscience, 1992 - Elsevier
Vital staining and routine histological analyses of mouse embryos 12 h after acute maternal
ethanol administration (2.9 g/kg) illustrated that selected neuronal cell populations are killed …
ethanol administration (2.9 g/kg) illustrated that selected neuronal cell populations are killed …
Fetal alcohol syndrome at the cellular level
J Olney - Addiction biology, 2004 - Wiley Online Library
A single exposure of infant rats or mice to ethanol during synaptogenesis (mid to late
pregnancy for humans) can cause developing neurons to commit suicide (die by apoptosis) …
pregnancy for humans) can cause developing neurons to commit suicide (die by apoptosis) …
Stage‐dependent effects of ethanol on cranial neural crest cell development: partial basis for the phenotypic variations observed in fetal alcohol syndrome
MM Cartwright, SM Smith - Alcoholism: Clinical and …, 1995 - Wiley Online Library
Fetal alcohol syndrome (FAS) is characterized by growth retardation, mental deficiencies,
and numerous craniofacial and neuronal anomalies; the type and severity of these defects …
and numerous craniofacial and neuronal anomalies; the type and severity of these defects …
Prenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development
G Wang, E Bieberich - Cell death & disease, 2010 - nature.com
Fetal alcohol syndrome (FAS) is caused by maternal alcohol consumption during
pregnancy. The reason why specific embryonic tissues are sensitive toward ethanol is not …
pregnancy. The reason why specific embryonic tissues are sensitive toward ethanol is not …