Abstract Purpose of Review This is an era where we have significantly advanced the
understanding of the genetic architecture of schizophrenia. In this review, we consider how …

Schizophrenia is a devastating mental disorder. The level of risk in the general population is
sustained by the persistence of social, environmental and biological factors, as well as their …

We present an overview of current progress and future directions in the molecular genetics
of schizophrenia. We review linkage studies, involving the genome-wide scan of …

Objective: The authors used a custom array of 1,536 single-nucleotide polymorphisms
(SNPs) to interrogate 94 functionally relevant candidate genes for schizophrenia and identify …

More than a century since the delineation of dementia praecox by Kraepelin, the etiology,
neuropathology and pathophysiology of schizophrenia remain elusive. Despite the …

Schizophrenia is a severe, complex mental disorder characterized by a combination of
positive symptoms, negative symptoms, and impaired cognitive function. Schizophrenia is …

A novel phenotyping strategy in schizophrenia, targeting different neurocognitive domains,
neurobehavioral features, and selected personality traits, has allowed us to identify a …

Schizophrenia is a highly polygenic brain disorder. The main hypothesis for disease etiology
in schizophrenia primarily focuses on the role of dysfunctional synaptic transmission …

Future work is encouraged to address whether each of these neural system dysfunctions are
under the influence of a partially distinct set of genes, to elucidate the manner in which …

Effective treatment for schizophrenia is still an unmet clinical need. Alleviating problems
associated with cognitive impairment and finding the root of the disease remain priorities for …