Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress

B Okiljević, N Martić, S Govedarica, B Andrejić Višnjić… - Pharmaceutics, 2024 - mdpi.com
Silymarin, derived from Silybum marianum, has been used in traditional medicine for various
ailments. In this study, the cardioprotective and hepatoprotective effects of silymarin against …

Protective effect of silymarin on oxidative stress in rat brain

C Nencini, G Giorgi, L Micheli - Phytomedicine, 2007 - Elsevier
Brain is susceptible to oxidative stress and it is associated with age-related brain
dysfunction. Previously, we have pointed out a dramatic decrease of glutathione levels in the …

Silymarin: A promising cardioprotective agent

Z Zalat, N Kohaf, M Alm El-Din, H Elewa… - … and Medical Sciences, 2021 - journals.ekb.eg
Silymarin 'milk thistle'(Silybum marianum) plant, has been used for years for treatment of
different diseases such as liver and gallbladder disorders, protecting liver against snake bite …

Silymarin prevents acetaminophen-induced hepatotoxicity in mice

Z Papackova, M Heczkova, H Dankova, E Sticova… - PloS one, 2018 - journals.plos.org
Acetaminophen or paracetamol (APAP) overdose is a common cause of liver injury.
Silymarin (SLM) is a hepatoprotective agent widely used for treating liver injury of different …

[PDF][PDF] Preventive effect of novel nanomicelle of silymarin on liver injury induced by carbon tetrachloride in rat.

YS Isfahani, A Aslani, MR Memarzadeh, MH Aarabi - 2021 - sid.ir
ABSTRACT Background and Aim: Silymarin is used for the treatment of liver disease due to
its hepatoprotective effects. however, the use of its extract is limited due to poor aqueous …

Silymarin modulates the oxidant–antioxidant imbalance during diethylnitrosamine induced oxidative stress in rats

K Pradeep, CVR Mohan, K Gobianand… - European journal of …, 2007 - Elsevier
Oxidative stress is a common mechanism contributing to initiation and progression of
hepatic damage in a variety of liver disorders. Hence, there is a great demand for the …

Silymarin, the antioxidant component and Silybum marianum extracts prevent liver damage

E Shaker, H Mahmoud, S Mnaa - Food and Chemical Toxicology, 2010 - Elsevier
Liver disorders are one of the common recent problems affects on the human health. These
disorders due to many environmental polluted sources. Many herbal, medicinal and …

Silymarin prevents restraint stress-induced acute liver injury by ameliorating oxidative stress and reducing inflammatory response

SH Kim, DS Oh, JY Oh, TG Son, DY Yuk, YS Jung - Molecules, 2016 - mdpi.com
Silymarin is a flavonoid extracted from the milk thistle Silybum marianum. It has been
reported to prevent liver injuries induced by various chemicals or toxins. Our recent study …

[PDF][PDF] Hepatoprotektif bir ajan: Silymarin

N Kocaman, DÖ Dabak - Firat Med J, 2015 - firattipdergisi.com
Silymarin is a purified extract from the seeds of Silybum marinum L.(Asteraceae) also called
“milk thistle”. Silymarin is widely used as a hepatoprotectant in the treatment of various liver …

[HTML][HTML] Protective effect of silymarin against chemical-induced cardiotoxicity

BM Razavi, G Karimi - Iranian journal of basic medical sciences, 2016 - ncbi.nlm.nih.gov
Cardiac disorders remain one of the most important causes of death in the world. Oxidative
stress has been suggested as one of the molecular mechanisms involved in drug-induced …