Developmental pathways to amygdala-prefrontal function and internalizing symptoms in adolescence
Early life stress (ELS) and function of the hypothalamic-pituitary-adrenal axis predict later
psychopathology. Animal studies and cross-sectional human studies suggest that this …
psychopathology. Animal studies and cross-sectional human studies suggest that this …
Amygdala–medial prefrontal cortex connectivity relates to stress and mental health in early childhood
AT Park, JA Leonard, PK Saxler, AB Cyr… - Social Cognitive and …, 2018 - academic.oup.com
Early life stress has been associated with disrupted functional connectivity between the
amygdala and medial prefrontal cortex (mPFC), but it is unknown how early in development …
amygdala and medial prefrontal cortex (mPFC), but it is unknown how early in development …
Early developmental emergence of human amygdala–prefrontal connectivity after maternal deprivation
DG Gee, LJ Gabard-Durnam… - Proceedings of the …, 2013 - National Acad Sciences
Under typical conditions, medial prefrontal cortex (mPFC) connections with the amygdala
are immature during childhood and become adult-like during adolescence. Rodent models …
are immature during childhood and become adult-like during adolescence. Rodent models …
[HTML][HTML] Early childhood stress is associated with blunted development of ventral tegmental area functional connectivity
Early life stress increases risk for later psychopathology, due in part to changes in
dopaminergic brain systems that support reward processing and motivation. Work in animals …
dopaminergic brain systems that support reward processing and motivation. Work in animals …
Development of amygdala functional connectivity during infancy and its relationship with 4-year behavioral outcomes
AP Salzwedel, RL Stephens, BD Goldman… - Biological Psychiatry …, 2019 - Elsevier
Background The amygdala represents a core node in the human brain's emotional signal
processing circuitry. Given its critical role, both the typical and atypical functional connectivity …
processing circuitry. Given its critical role, both the typical and atypical functional connectivity …
Development of white matter microstructure and intrinsic functional connectivity between the amygdala and ventromedial prefrontal cortex: associations with anxiety …
Background Connectivity between the amygdala and ventromedial prefrontal cortex
(vmPFC) is compromised in multiple psychiatric disorders, many of which emerge during …
(vmPFC) is compromised in multiple psychiatric disorders, many of which emerge during …
Childhood stress, grown-up brain networks: corticolimbic correlates of threat-related early life stress and adult stress response
BackgroundExposure to threat-related early life stress (ELS) has been related to
vulnerability for stress-related disorders in adulthood, putatively via disrupted corticolimbic …
vulnerability for stress-related disorders in adulthood, putatively via disrupted corticolimbic …
Amygdala hyper-connectivity in a mouse model of unpredictable early life stress
FK Johnson, JC Delpech, GJ Thompson, L Wei… - Translational …, 2018 - nature.com
Childhood maltreatment is associated with a wide range of psychopathologies including
anxiety that emerge in childhood and in many cases persist in adulthood. Increased …
anxiety that emerge in childhood and in many cases persist in adulthood. Increased …
The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence
Early life stress (ELS) is a significant risk factor for the emergence of internalizing problems
in adolescence. Beginning in adolescence, females are twice as likely as males to …
in adolescence. Beginning in adolescence, females are twice as likely as males to …
[HTML][HTML] Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants
Stressful experiences are linked to neurodevelopment. There is growing interest in the role
of stress in the connectivity between the amygdala and medial prefrontal cortex (mPFC), a …
of stress in the connectivity between the amygdala and medial prefrontal cortex (mPFC), a …