Glioblastoma (GBM) is the most common primary brain tumor in adults and shows a very
malignant behavior. Current standard therapy includes radical tumor extirpation followed by …

Background Predictive molecular biomarkers to select optimal treatment for patients with
glioblastoma and other cancers are lacking. New strategies are needed when large …

Background Glioblastoma patients administered standard therapies, comprising maximal
surgical resection, radiation therapy with concomitant and adjuvant temozolomide, have a …

Background Although implementation of temozolomide (TMZ) as a part of primary therapy
for glioblastoma multiforme (GBM) has resulted in improved patient survival, the disease is …

Uncertainty exists about the adequate treatment of adult patients with unresectable, primary,
biopsy-proven glioblastoma multiforme (GBM), because the different options for this group of …

AIM To investigate machine learning based models combining clinical, radiomic, and
molecular information to distinguish between early true progression (tPD) and …

Low-grade gliomas (LGGs) are brain tumors characterized by their slow growth and
infiltrative nature. Treatment options for these tumors are surgery, radiation therapy and …

Objectives As a few types of glioma, young high-risk low-grade gliomas (HRLGGs) have
higher requirements for postoperative quality of life. Although adjuvant chemotherapy with …

Since the development of the Radiation Therapy Oncology Group-Recursive Partitioning
Analysis (RTOG-RPA) risk classes for high-grade glioma, radiation therapy in combination …

Few population-based analyses have investigated survival change in glioblastoma
multiforme (GBM) patients treated with concomitant radiotherapy-temozolomide (RT-TMZ) …