OBJECTIVES: To assess the patterns of failure and prognostic factors in Brazilian patients
with glioblastoma multiforme (GBM) treated with radiotherapy (RT) and concurrent and …

Background and purpose To refine the recursive partitioning analysis (RPA) classification for
glioblastoma incorporating the MGMT methylation and IDH1 mutation status. Methods and …

This study aimed to investigate the performance of a deep learning-based survival-
prediction model, which predicts the overall survival (OS) time of glioblastoma patients who …

Introduction Despite aggressive treatment with chemoradiotherapy and maximum surgical
resection, survival in patients with glioblastoma (GBM) remains poor. Ongoing efforts are …

Background A randomised trial published by the European Organisation for Research and
Treatment of Cancer (EORTC) and the National Cancer Institute of Canada (NCIC) Clinical …

Results pAKT, c-met, and MGMT protein were each found to be significantly associated with
adverse outcome on multivariate analysis. These variables were combined with clinical and …

Background In 2005, maximum safe surgical resection, followed by radiotherapy with
concomitant temozolomide (TMZ), followed by adjuvant TMZ became the standard of care …

2012 Background: Current standard of care for newly diagnosed GBM includes trimodality
treatment followed by six cycles of adjuvant temozolomide (TMZ). We analysed the uptake of …

Background Glioblastoma (GBM) remains associated with a dismal prognosis despite
standard therapies. While population-level survival statistics are established, generating …

Results Between July 2000 and March 2002, a total of 573 patients were randomized by 85
institutions. Sixteen percent of patients had a biopsy only, and 84% had either partial (44%) …