We report herein synthesis of a series of 4‐aminoquinoline‐1, 2, 3‐triazole and 4‐
aminoquinoline‐1, 2, 3‐triazole‐1, 3, 5‐triazine hybrids and evaluate their antimalarial …

Malaria is one of the most prevalent parasitic diseases in the world. The global importance
of this disease, current vector control limitations, and the absence of an effective vaccine …

The emergence and rapid spread of chloroquine resistant strains of Plasmodium falciparum
has dramatically reduced the chemotherapeutic options. Towards this goal, a series of new …

A systematic chemical modification in the triazine moiety covalently attached via suitable
linkers to 4‐amino‐7‐chloroquinolines yielded a series of new 7‐chloro‐4‐aminoquinoline …

A series of isoxazole and triazole derivatives, with interesting bioactive scaffolds, were
examined for their in vitro antibacterial, antifungal, and antiprotozoal activities. These …

Abstract Novel 4‐amino‐7‐chloroquinoline‐based 1, 2, 3‐triazole hybrids were synthesised
in good yields by CuI‐catalysed Huisgen 1, 3‐dipolar cycloaddition reactions of 2‐azido‐N …

A novel class of hybrid 4-anilinoquinoline triazines have been synthesized and evaluated in
vitro for their antimalarial activity against CQ-sensitive 3D7 strain of P. falciparum as well as …

A class of hybrid molecules consisting of 4-aminoquinoline and pyrimidine were synthesized
and tested for antimalarial activity against both chloroquine (CQ)-sensitive (D6) and …

Abstract A series of 1H-1, 2, 3-triazole/acylhydrazide-tethered tetrahydro-β-carboline-4-
aminoquinoline conjugates was synthesized with an aim to study their anti-plasmodial …

In the search of novel chemotherapeutic agents for emerging drug resistant parasites, the
hybridization approaches have successfully emerged as an efficient tool in malarial …