Background: Opioids are natural, semisynthetic, or synthetic substances that act on opioid
receptors in the central nervous system. Clinically, they are prescribed for pain …

Aims. To characterize the population of drug users consulting the Emergency Room (ER) of
a university hospital with acute opiate overdose (AOO) and to assess rate of referral to …

Objectives: Review the current opioid epidemic in the USA. Describe the mode of action of
the opiates. Summarize ways to prevent and manage opiate toxicity and overdose. Explain …

Objectives: To investigate clinical outcomes in a cohort of opioid overdose patients treated in
an out‐of‐hospital urban setting noted for a high prevalence of IV opioid use. Methods: A …

Opiates extracted from the poppy plant (Papaver somniferum) have been used
recreationally and medicinally for millennia. Opiates belong to the larger class of drugs, the …

Acute opioid intoxication and overdose are common causes of presentation to emergency
departments. Although naloxone, a pure opioid antagonist, has been available for many …

Management of Opioid Analgesic Overdose | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Opioids are widely used for analgesic purposes. If taken as prescribed, they are safe and
effective. Overdosing, however, can cause coma and life-threatening respiratory depression …

Objective: An increasing and serious heroin overdose problem in Oslo has mandated the
increasing out-of-hospital use of naloxone administered by paramedics. The aim of this …

Over 2 million Americans misuse prescription or illicitly obtained opioids, and opioid
overdose deaths rose to a record 47,600 in 2017, representing a nearly 600% increase in …