Molecular basis of the anti-inflammatory effects of terpenoids

S Hortelano - Inflammation & Allergy-Drug Targets (Formerly …, 2009 - ingentaconnect.com
Natural products play a significant role in human health in relation to the prevention and
treatment of inflammatory conditions. Among them, terpenoids (also referred to as terpenes) …

Terpenoids: natural inhibitors of NF-κB signaling with anti-inflammatory and anticancer potential

A Salminen, M Lehtonen, T Suuronen… - Cellular and Molecular …, 2008 - Springer
Traditional medicine has been a fertile source for revealing novel lead molecules for modern
drug discovery. In plants, terpenoids represent a chemical defense against environmental …

Natural terpenoids with anti-inflammatory activities: Potential leads for anti-inflammatory drug discovery

J Ge, Z Liu, Z Zhong, L Wang, X Zhuo, J Li, X Jiang… - Bioorganic …, 2022 - Elsevier
Natural products are mainly secondary metabolites produced by plants, microorganisms,
and animals, which are still abundant in modern drug discovery. Terpenoids are the most …

Labdane diterpenoids as potential anti-inflammatory agents

QTN Tran, WSF Wong, CLL Chai - Pharmacological research, 2017 - Elsevier
The search for new anti-inflammatory agents is challenging due to the complexity of the
inflammatory process and its role in host defense. Over the past few decades, a significant …

Therapeutic applications of terpenes on inflammatory diseases

ML Del Prado-Audelo, H Cortés… - Frontiers in …, 2021 - frontiersin.org
In the last decades, the search for natural products with biological applications as alternative
treatments for several inflammatory diseases has increased. In this respect, terpenes are a …

[HTML][HTML] Monoterpenes modulating cytokines-A review

JSS Quintans, S Shanmugam, L Heimfarth… - Food and chemical …, 2019 - Elsevier
Inflammatory response can be driven by cytokine production and is a pivotal target in the
management of inflammatory diseases. Monoterpenes have shown that promising profile as …

Molecular mechanism underlying anti-inflammatory and anti-allergic activities of phytochemicals: an update

Y Bellik, L Boukraâ, HA Alzahrani, BA Bakhotmah… - Molecules, 2012 - mdpi.com
The resort worldwide to edible medicinal plants for medical care has increased significantly
during the last few years. Currently, there is a renewed interest in the search for new …

Supression of inflammatory responses by labdane-type diterpenoids

N Girón, PG Través, B Rodríguez… - Toxicology and applied …, 2008 - Elsevier
A series of 11 labdane-type diterpenoids (1–11) with various patterns of substitution were
tested for potential anti-inflammatory activity. Of these compounds, 4 and 11 were selected …

The antiinflammatory potential of flavonoids: Mechanistic aspects

MD Catarino, O Talhi, A Rabahi, AMS Silva… - Studies in natural …, 2016 - Elsevier
Flavonoids are a subclass of phenolic compounds that occur ubiquitously in food plants and
vegetables. This class of compounds shares a common 15-carbon structure represented by …

Intracellular signaling pathways modulated by phenolic compounds: application for new anti-inflammatory drugs discovery

G Costa, V Francisco, MC Lopes… - Current medicinal …, 2012 - ingentaconnect.com
Extensive research within the last two decades revealed that most chronic illnesses,
including cancer, neurological, autoimmune and cardiovascular diseases are mediated …