Childhood maltreatment is a key risk factor for poor mental and physical health. Recently,
variation in epigenetic processes, such as DNA methylation, has emerged as a potential …

Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …

BACKGROUND: Child abuse is highly prevalent and associated with increased risk for a
range of health problems, including cancer, cardiovascular disease, diabetes, psychiatric …

Epigenetic mechanisms are potential mediators of the physiological response to abuse by
altering the genetic predisposition of the cellular response to the environment, leading to …

Childhood maltreatment is highly prevalent and serves as a risk factor for mental and
physical disorders. Self-reported childhood maltreatment appears heritable, but the specific …

DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …

Background Childhood abuse is associated with increased adult disease risk, suggesting
that processes acting over the long-term, such as epigenetic regulation of gene activity, may …

Objective: DNA methylation has been proposed as an epigenetic mechanism by which early-
life experiences become “embedded” in the genome and alter transcriptional processes to …

Child maltreatment (CM) encompasses sexual abuse, physical abuse, emotional abuse,
neglect, and exposure to domestic and family violence. Epigenetic research investigating …

Childhood adversity affects later health, but the underlying molecular mechanisms are
unclear. Although there is some evidence from animal models and case-control studies of a …