This study compared the neuroprotective efficacy of three antioxidants—the plant-derived
carnosic acid (CA), and two synthetic free radical scavengers: edaravone (ED) and ebselen …

The effects of aqueous extracts of Celastrus paniculatus (CP) seeds were shown to have
antioxidant properties in rats. In the study reported here, we have investigated the free …

Seed oil of Celastrus paniculatus Willd.(CP) has been reported to improve memory and the
methanolic extract (ME) of CP was shown to exhibit free-radical-scavenging properties and …

One of the major features of neurodegenerative disease is the selective vulnerability of
different neuronal populations that are affected in a progressive and often stereotyped …

Abstract Carnosic acid (CA; C 20 H 28 O 4), a phenolic diterpene characterized as an ortho-
dihydroquinone-type molecule, is a pro-electrophile agent that becomes an electrophile …

In a previous study, we found that carnosic acid (CA) protected cortical neurons by activating
the Keap1/Nrf2 pathway, which activation was initiated by S-alkylation of the critical cysteine …

The effect of ad libitum oral-administration of (-) catechin solution on ischemia-reperfusion-
induced cell death of hippocampal CA1 in the gerbil was histologically examined. When (-) …

As human life expectancy has increased, so too has the incidence of age-related
neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and …

Abstract Trans-caryophyllene (TC), a component of essential oil found in many flowering
plants, has shown its neuroprotective effects in various neurological disorders. However, the …

Ischemia/hypoxia induces oxidative stress which is associated with neurodegenerative
diseases. The present study investigated protective mechanism of carnosic acid (CA) on …